Systemic levels of glyceryl trinitrate following topical application to the anoderm do not correlate with the measured reduction in anal pressure

British Journal of Surgery

Volumn 88, Issue 12, 2001, Pages 1613-1616

  Jonas, M ^a   Barrett, D A ^a   Shaw, P N ^a   Scholefield, J H ^a  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCERYL TRINITRATE;

ADULT; AGED; ANUS; ANUS SPHINCTER; ARTICLE; BLOOD PRESSURE MEASUREMENT; BLOOD SAMPLING; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; DRUG BLOOD LEVEL; DRUG DETERMINATION; FEMALE; HEADACHE; HUMAN; MALE; MANOMETRY; NORMAL HUMAN; PRESSURE; PRIORITY JOURNAL; PULSE RATE; SYSTOLIC BLOOD PRESSURE;

ABSORPTION; ADMINISTRATION, TOPICAL; ADULT; AGED; ANAL CANAL; BLOOD PRESSURE; FEMALE; HEADACHE; HUMANS; MALE; MANOMETRY; MIDDLE AGED; NITROGLYCERIN; OINTMENTS; PRESSURE; VASODILATOR AGENTS;

EID: 0035205533     PISSN: 00071323     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.0007-1323.2001.01932.x     Document Type: Article

References (16)

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9. Clinical pharmacokinetics of glyceryl trinitrate following the use of systemic and topical preparations
10. Nitroglycerin in situ reduces upper anal canal pressure
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13. Nifedipine for local use in conservative treatment of anal fissures: Preliminary results of a multicenter study
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15. Pharmacological characterization of neurogenic responses of the sheep isolated internal anal sphincter
16. Comparison of the effects of glyceryl trinitrate (GTN) and diltiazem on isolated sheep internal anal sphincter