A practical preparation of methyl 2-methoxy-6-methylaminopyridine-3-carboxylate from 2,6-dichloro-3-trifluoromethylpyridine

Chemical and Pharmaceutical Bulletin

Volumn 49, Issue 12, 2001, Pages 1621-1627

  Horikawa, T ^a   Hirokawa, Y ^a   Kato, S ^a  

^a DAINIPPON SUMITOMO PHARMA CO LTD   (Japan)

Author keywords

2,6 dichloro 3 trifluoropyridine; 2 chloro 6 methylamino 3 trimethoxymethyl pyridine; Antiemetic agent; Dopamine D2, D3 receptor; Regioselective synthesis; Serotonin 3 receptor

Indexed keywords

ANTIEMETIC AGENT; CARBONYL DERIVATIVE; DOMPERIDONE; METHYL 2 METHOXY 6 METHYLAMINOPYRIDINE 3 CARBOXYLATE; PICOLINE DERIVATIVE; SODIUM DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; DRUG SYNTHESIS; HYDROLYSIS; ISOMER; PROTON NUCLEAR MAGNETIC RESONANCE; REACTION ANALYSIS; STEREOCHEMISTRY;

ANTIEMETICS; AZEPINES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; INDICATORS AND REAGENTS; MAGNETIC RESONANCE SPECTROSCOPY; MASS SPECTROMETRY; NICOTINIC ACIDS; PYRIDINES; SPECTROMETRY, MASS, FAST ATOM BOMBARDMENT; SPECTROPHOTOMETRY, INFRARED;

EID: 0035205301     PISSN: 00092363     EISSN: None     Source Type: Journal    
DOI: 10.1248/cpb.49.1621     Document Type: Article

References (18)