Asymmetric biosynthesis of key aromatic intermediates in the synthesis of an endothelin receptor antagonist

Biocatalysis and Biotransformation

Volumn 19, Issue 4, 2001, Pages 267-279

  Krulewicz, Barbara ^a   Tschaen, David ^a   Deine, Paul ^a   Lee, Steven S ^a   Roberge, Christopher ^a   Greasham, Randolph ^a   Chartrain, Michel ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Bioconversion; Bioprocess; Bioreduction; Fermentation; Microbial screening

Indexed keywords

BIOREACTORS; BIOTECHNOLOGY; ESTERS; KETONES; SYNTHESIS (CHEMICAL);

AROMATIC INTERMEDIATES;

BIOSYNTHESIS;

ALCOHOL; AROMATIC COMPOUND; ENDOTHELIN RECEPTOR ANTAGONIST; ESTER; KETONE;

ARTICLE; BIOCATALYST; BIOPROCESS; BIOREACTOR; BIOTRANSFORMATION; CHEMICAL MODIFICATION; CHIRALITY; CHLORINATION; CONTROLLED STUDY; DRUG HYDROLYSIS; DRUG SYNTHESIS; ENANTIOMER; ESTERIFICATION; EXPERIMENTATION; LABORATORY; MICROBIOLOGICAL EXAMINATION; NONHUMAN; PICHIA; RACEMIC MIXTURE; RHODOTORULA;

EID: 0035203285     PISSN: 10242422     EISSN: None     Source Type: Journal    
DOI: 10.3109/10242420109003644     Document Type: Article

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