c-Src and HSP72 interact in ATP-depleted renal epithelial cells

American Journal of Physiology - Cell Physiology

Volumn 281, Issue 5 50-5, 2001, Pages

  Wang, Y H ^a   Li, F ^b   Schwartz, J H ^b   Flint, P J ^b   Borkan, S C ^b,c  

^a TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b BOSTON MEDICAL CENTER   (United States)

^c BOSTON UNIVERSITY   (United States)

Author keywords

Cytoskeleton; Heat shock protein 70; Ischemia; Paxillin; Triton X 100; Vinculin; Yes kinase; catenin

Indexed keywords

ADENOSINE TRIPHOSPHATE; BETA CATENIN; HEAT SHOCK PROTEIN 72; PAXILLIN; PROTEIN TYROSINE KINASE; VINCULIN;

ANIMAL CELL; ARTICLE; CELL ADHESION; CELL CONTACT; CELL PROTECTION; CONTROLLED STUDY; ENZYME ACTIVITY; EXTRACELLULAR MATRIX; GENE ACTIVATION; HEAT STRESS; IMMUNOPRECIPITATION; IN VITRO STUDY; ISCHEMIA; KIDNEY EPITHELIUM; KIDNEY FUNCTION; MAMMAL CELL; NONHUMAN; ONCOGENE SRC; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION;

EID: 0035200280     PISSN: 03636143     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpcell.2001.281.5.c1667     Document Type: Article

References (62)

1. Cadherin-catenin complex: Protein interaction and their implications for cadherin function
2. Oxidative stress activates extracellular signal-regulated kinases through Src and Ras in cultured cardiac myocytes of neonatal rats
3. Tight junctions and the molecular basis of regulation of paracellular permeability
4. yes
5. ATP depletion: A novel method to study junctional properties in epithelial tissues. I. Rearrangement of the actin cytoskeleton
6. Interaction of HSP 70 with newly synthesized proteins: Implications for protein folding and assembly events
7. Heat stress ameliorates ATP depletion-induced sublethal injury in mouse proximal tubule cells
8. Acute renal failure
9. Tight junctions: Guardians of the paracellular pathway
10. Regulation, substrates and functions of Src
11. HSP 90 and Co-a holding for folding
12. FAK accompanies cell adhesion to extracellular matrix: A role in cytoskeletal assembly
13. The molecular organization of tight junctions
14. Integrin-mediated signals regulated by members of the Rho family of GTPases
15. The when and how of Src regulation
16. Tyrosine phosphorylation and cadherin/catenin function
17. The mammalian ultraviolet response is triggered by activation of Src tyrosine kinase
18. Signaling by the Src family kinases: Lessons learned from DNA tumor viruses
19. Translocation of Src kinase to the cell periphery is mediated by the actin cytoskeleton under the control of the Rho family of small proteins
20. Identification of a regulatory motifin HSP 70 affects ATPase activity, substrate binding and interaction with HDJ-1
21. Deletions in the SH2 domain of p60v-src prevent association with the detergent-insoluble cellular matrix
22. Protein aggregates as primary and characteristic reaction to various stresses
23. HSP70 prevents activation of stress kinases: A novel pathway of cellular thermotolerance
24. Rho GTPase signaling regulates tight junction assembly and protects tight junctions during ATP depletion
25. Agonist-stimulated cytoskeletal reorganization and signal transduction at focal adhesions in vascular smooth muscle cells requires c-Src
26. Tyrosine phosphorylation regulates the adhesions of ras-transformed breast epithelia
27. 524 influences nuclear accumulation of HSP72 with heat stress
28. Functional and cytoskeletal changes induced by sublethal injury in epithelial cells
29. Association between a transmembrane protein tyrosine phosphatase and the cadherin-catenin complex
30. NSAID-induced apoptosis in Rous sarcoma virus-transformed chicken embryo fibroblasts is dependent on v-src and c-myc and is inhibited by bcl-2
31. Over-expression of the rat inducible 70 kD heat stress protein in a transgenic mouse increases the resistance of the heart to ischemic injury
32. Cadherin-mediated cell-cell adhesion is perturbed by v-src tyrosine phosphorylation in metastatic fibroblasts
33. Protein-damaging stresses activate c-Jun N-terminal kinase via inhibition of its dephosphorylation: A novel pathway controlled by HSP72
34. Expression of inducible stress protein 70 in rat myogenic cells confers protection against simulated ischemia-induced injury
35. Integrin function: Molecular hierarchies of cytoskeletal and signaling molecules
36. Putting the actin cytoskeleton into perspective: Pathophysiology of acute renal failure
37. Activation of Src family kinases in Neu-induced mammary tumors correlates with their association with distinct sets of tyrosine phosphorylated proteins in vivo
38. Dynamics of membrane-skeleton (fodrin) organization during development of polarity in Madin-Darby canine kidney epithelial cells
39. Src family protein tyrosine kinases: Cooperating with growth factor and adhesion signaling pathways
40. cas) are elevated in cytoskeleton-associated fractions following adhesion and Src-transformation
41. Acute loss of cell-cell communication caused by G-protein coupled receptors: A critical role for c-Src
42. Dissociation of tubular cell detachment and tubular cell death in clinical and experimental "acute tubular necrosis"
43. Inhibition of cell spreading by expression of the C-terminal domain of focal adhesion protein kinase (FAK) is rescued by co-expression of Src or catalytically inactive FAK: A role for paxillin tyrosine phosphorylation
44. Phosphorylation of p125FAK and paxillin focal adhesion proteins in src-transformed cells with different metastatic capacity
45. 2 stimulation
46. Anchorage dependence, integrins and apoptosis
47. Complex formation with focal adhesion kinase: A mechanism to regulate activity and subcellular localization of Src kinases
48. ATP depletion increases tyrosine phosphorylation of β-catenin and plakoglobin in renal tubular cells
49. The many faces of Src: Multiple functions of a prototypic tyrosine kinase
50. Rescue of osteoclast function by transgeneic expression of kinase-deficient Src in src -/- mutant mice
51. Hypoxia and hypoxia/reoxygenation activate Src family tyrosine kinases and p21 in cultured cardiac myocytes
52. Evidence that tyrosine phosphorylation may increase tight junction permeability
53. Mechanisms of cellular injury in ischemic acute renal failure
54. Regulation of calcium-sensitive tyrosine kinase Pyk2 by angiotensin II in endothelial cells. Roles of Yes tyrosine kinase and tyrosine phosphatase SHP-2
55. Tight junction proteins form large complexes and associate with the cytoskeleton in an ATP depletion model for reversible junction assembly
56. In vivo and in vitro detachment of proximal tubular cells and F-actin damage: Consequences for renal function
57. Overexpression of c-Src enhances cell-matrix adhesion and cell migration in PDGF-stimulated NIHT3 fibroblasts
58. Prior heat stress enhances survival of renal epithelial cells after ATP depletion
59. Prior heat stress inhibits apoptosis in adenosine trisphosphate-depleted renal tubular cells
60. Maturation of the tyrosine kinase c-Src as a kinase and as a substrate depends on the molecular chaperone HSP90
61. Inactivation of c-Yes tyrosine kinase by elevation of intracellular calcium levels
62. Cadmium is more toxic to LLC-PK1 cells than to MDCK cells acting on the cadherin-catenin complex