Cardiac electrophysiologic and hemodynamic effects of sildenafil, a PDE5 inhibitor, in anesthetized dogs

Journal of Cardiovascular Pharmacology

Volumn 38, Issue 6, 2001, Pages 940-946

  Sugiyama, Atsushi ^a   Satoh, Yoshioki ^a   Shiina, Hiroyuki ^a   Takahara, Akira ^a   Yoneyama, Masahiko ^a   Hashimoto, Keitaro ^a  

^a UNIVERSITY OF YAMANASHI   (Japan)

Author keywords

Effective refractory period; Ikr; Monophasic action potential; Repolarization; Sildenafil

Indexed keywords

HALOTHANE; PHOSPHODIESTERASE INHIBITOR; SILDENAFIL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHRONOTROPISM; CONTROLLED STUDY; DOG; DOSE RESPONSE; DRUG BLOOD LEVEL; ELECTROCARDIOGRAM; HEART ELECTROPHYSIOLOGY; HEART MUSCLE POTENTIAL; HEART REPOLARIZATION; HEMODYNAMICS; IN VIVO STUDY; NONHUMAN; PRIORITY JOURNAL; REFRACTORY PERIOD; VASCULAR RESISTANCE;

3',5'-CYCLIC-GMP PHOSPHODIESTERASE; ACTION POTENTIALS; ANESTHESIA; ANIMALS; BLOOD PRESSURE; BUNDLE OF HIS; CARDIAC PACING, ARTIFICIAL; DOGS; ELECTRIC CONDUCTIVITY; ELECTROCARDIOGRAPHY; FEMALE; HEART RATE; HEMODYNAMIC PROCESSES; MALE; PHOSPHODIESTERASE INHIBITORS; PIPERAZINES; POTASSIUM CHANNEL BLOCKERS; REFRACTORY PERIOD, ELECTROPHYSIOLOGICAL; VASCULAR RESISTANCE; VENTRICULAR FUNCTION, RIGHT; VENTRICULAR PRESSURE;

EID: 0035200232     PISSN: 01602446     EISSN: None     Source Type: Journal    
DOI: 10.1097/00005344-200112000-00016     Document Type: Article

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