Serum YKL-40 is associated with osteoarthritis and atherosclerosis in nonhuman primates

Clinical Chemistry

Volumn 47, Issue 12, 2001, Pages 2159-2161

  Register, T C ^a   Carlson, C S ^a   Adams, M R ^a  

^a WAKE FOREST SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOPROTEIN GP 39; PROTEIN YKL 40; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORONARY ARTERY ATHEROSCLEROSIS; DISEASE ASSOCIATION; DISEASE MARKER; DISEASE SEVERITY; NONHUMAN; OSTEOARTHRITIS; PRIMATE; PROTEIN BLOOD LEVEL; SYNOVIAL FLUID;

ANIMALIA; PRIMATES;

EID: 0035197246     PISSN: 00099147     EISSN: None     Source Type: Journal    
DOI: 10.1093/clinchem/47.12.2159     Document Type: Article

References (29)

1. Arthritis prevalence and activity limitations - United States
2. Osteoarthritis in cynomolgus macaques: A primate model of naturally occurring disease
3. Osteoarthritis in cynomolgus macaques. II. Detection of modulated proteoglycan epitopes in cartilage and synovial fluid
4. Osteoarthritis in cynomolgus macaques. III: Effects of age, gender, and subchondral bone thickness on the severity of disease
5. A new biochemical marker for joint injury. Analysis of YKL-40 in serum and synovial fluid
6. Serum YKL-40 levels in healthy children and adults. Comparison with serum and synovial fluid levels of YKL-40 in patients with osteoarthritis or trauma of the knee joint
7. Serum YKL-40 concentrations in patients with rheumatoid arthritis: Relation to disease activity
8. Chondrex: New marker of joint disease
9. Serum levels of YKL-40 and C reactive protein in patients with hip osteoarthritis and healthy subjects: A cross sectional study
10. Human cartilage gp-39, a major secretory product of articular chondrocytes and synovial cells, is a mammalian member of a chitinase protein family
11. Identification of proteins secreted by human osteoblastic cells in culture
12. Differential screening identifies genetic markers of monocyte to macrophage maturation
13. Induction and expression of human cartilage glycoprotein 39 in rheumatoid inflammatory and peripheral blood monocyte-derived macrophages
14. Strong induction of members of the chitinase family of proteins in atherosclerosis: Chitotriosidase and human cartilage gp-39 expressed in lesion macrophages
15. Chitotriosidase, a chitinase, and the 39-kDa human cartilage glycoprotein, a chitin-binding lectin, are homologs of family 18 glycosyl hydrolases secreted by human macrophages
16. Identification of a 38-kDa heparin-binding glycoprotein (gp38 k) in differentiating vascular smooth muscle cells as a member of a group of proteins associated with tissue remodeling
17. Medroxyprogesterone acetate antagonizes inhibitory effects of conjugated equine estrogens on coronary artery atherosclerosis
18. Tamoxifen inhibits arterial accumulation of LDL degradation products and progression of coronary artery atherosclerosis in monkeys
19. An introduction to the pathophysiology of osteoarthritis
20. Proteoglycans structure and function as related to atherosclerosis
21. A proposed structure of chondroitin 6-sulfate proteoglycan of human normal and adjacent atherosclerotic plaque
22. Plasma low density lipoprotein accumulation in aortas of hypercholesterolemic swine correlates with modifications in aortic glycosaminoglycan composition
23. Immunolocalization of proteoglycan types in aortas of pigeons with spontaneous or diet-induced atherosclerosis
24. Demonstration of a keratan sulfate containing proteoglycan in atherosclerotic aorta
25. Decreased amount and size of artery chondroitin sulfate proteoglycan-hyaluronic acid aggregate in atherosclerosis
26. Cartilage proteoglycan alterations in an experimentally induced model of rabbit osteoarthritis
27. Molecular identification of a putative human hyaluronan synthase
28. Cells expressing the DG42 gene from early Xenopus embryos synthesize hyaluronan
29. Biochemistry, histology and clinical uses of chitins and chitosans in wound healing