Hyal2 - Less active, but more versatile?

Matrix Biology

Volumn 20, Issue 8, 2001, Pages 509-514

  Lepperdinger, Günter ^a   Müllegger, Johannes ^a   Kreil, Günther ^b  

^a ERICH SCHMID INSTITUTE OF MATERIALS SCIENCE   (Austria)

^b EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

Author keywords

Hyal2; Hyaluronan; Hyaluronidase; Xenopus development

Indexed keywords

COMPLEMENTARY DNA; GLYCOPROTEIN; HYALURONIDASE; ISOENZYME; LYSOSOME ENZYME; POLYSACCHARIDE;

BRAIN; CELLULAR DISTRIBUTION; CHROMOSOME 3P; EMBRYO DEVELOPMENT; ENZYME ACTIVITY; GENE OVEREXPRESSION; GENE SILENCING; HUMAN; HYDROLYSIS; INFLAMMATION; METHYLATION; MOLECULAR WEIGHT; NONHUMAN; PH; POSTNATAL DEVELOPMENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN STRUCTURE; SEQUENCE HOMOLOGY; SHORT SURVEY; TISSUE DISTRIBUTION; TUMOR; VERTEBRATE; XENOPUS LAEVIS;

AMINO ACID SEQUENCE; ANIMALS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; HYALURONIC ACID; HYALURONOGLUCOSAMINIDASE; MICE; MOLECULAR SEQUENCE DATA; NEOPLASMS; SEQUENCE HOMOLOGY, AMINO ACID; TISSUE DISTRIBUTION; XENOPUS LAEVIS;

ANURA; VERTEBRATA; XENOPUS LAEVIS;

EID: 0035193894     PISSN: 0945053X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0945-053X(01)00170-6     Document Type: Short Survey

References (37)

1. Early changes in lung tissue hualuronan and hyaluronidase in bleomycin induced alveolitis in hamsters
2. In vitro mutagenesis of PH-20 hyaluronidase from human sperm
3. The PH-20 protein in cynomolgus macaque spermatozoa: Identification of two different forms exhibiting hyaluronidase activity
4. The dual function of GPI-anchored PH-20: Hyaluronidase and intracellular signaling
5. Purification of CpG islands using a methylated DNA binding column
6. The hyaluronidase gene HYAL1 maps to chromosome 3p21.2-p21.3 in human and 9F1-F2 in mouse, a conserved candidate tumor suppressor locus
7. A homozygous deletion on chromosome 3 in a small cell lung cancer cell line correlates with a region of tumor suppressor activity
8. The growth rate of two transplantable murine tumors, 3LL lung carcinoma and B16F10 melanoma, is influenced by Hyal-1, a locus determining hyaluronidase levels and polymorphism
9. Dynamic role of hyaluronan in connective tissue activation and inflammation
10. Bee venom hyaluronidase is homologous to a membrane protein of mammalian sperm
11. Expression pattern of a novel hyaluronidase during Xenopus embryogenesis
12. The amino-terminal sequence of bee venom hyaluronidase
13. The purification and characterisation of hyaluronidase from the venom of the honey bee, Apis mellifera
14. Synthesis of hyaluronan of distinctly different chain length is regulated by differential expression of Xhas1 and 2 during early development of Xenopus laevis
15. Hyaluronidases - A group of neglected enzymes
16. cDNA cloning reveals the molecular structure of a sperm surface protein, Ph-20, involved in sperm-egg adhesion and the wide distribution of its gene among mammals
17. Serum hyaluronan as a disease marker
18. HYAL2, a human gene expressed in many cells, encodes a lysosomal hyaluronidase with a novel type of specificity
19. Irradiation-induced expression of hyaluronan (HA) synthase 2 and hyaluronidase 2 genes in rat lung tissue accompanies active turnover of HA and induction of types I and III collagen gene expression
20. Expression of hyaluronidase by tumor cells induces angiogenesis in vivo
21. Sequence identity and antigenic cross-reactivity of white face hornet venom allergen, also a hyaluronidase, with other proteins
22. Crystal structure of hyaluronidase, a major allergen of bee venom
23. Hapten-labeled hyaluronan, a substrate to monitor hyaluronidase activity by enhanced chemiluminescence-assisted detection on filter blots
24. Hyaluronan is an abundant constituent of the extracellular matrix of Xenopus embryos
25. Hyaluronidase-2 overexpression accelerates intracerebral but not subcutaneous tumor formation of murine astrocytoma cells
26. A role for the migrating sperm surface antigen PH-20 in guinea pig sperm binding to the egg zona pellucida
27. Candidate tumor suppressor HYAL2 is a glycosylphosphatidylinositol (GPI)-anchored cell-surface receptor for jaagsiekte sheep retrovirus, the envelope protein of which mediates oncogenic transformation
28. Xenopus kidney hyaluronidase-1 (XKH1), a novel type of membrane-bound hyaluronidase solely degrades hyaluronan at neurtal pH
29. Accumulation and decay of DG42 gene products follow a gradient pattern during Xenopus embryogenesis
30. Cytokine regulation of human lung fibroblast hyaluronan (hyaluronic acid) production. Evidence for cytokine-regulated hyaluronan degradation and human lung fibroblast-derived hyaluronidase
31. Hyaluronate-independent metastatic behavior of CD44 variant-expressing pancreatic carcinoma cells
32. Structural organization and chromosomal localization of Hyal2, a gene encoding a lysosomal hyaluronidase
33. Hyaluronan in morphogenesis
34. Construction of a 600-kilobase cosmid clone contig and generation of a transcriptional map surrounding the lung cancer tumor suppressor gene (TSG) locus on human chromosome 3p21.3: Progress toward the isolation of a lung cancer TSG