Preoperative oral B vitamins prevent nitrous oxide-induced postoperative plasma homocysteine increases

Anesthesia and Analgesia

Volumn 93, Issue 6, 2001, Pages 1507-1510

  Badner, Neal H ^a,b   Freeman, Dave ^a   Spence, J David ^a  

^a UNIVERSITY OF WESTERN ONTARIO   (Canada)

^b LONDON HEALTH SCIENCES CENTRE   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CYANOCOBALAMIN; FENTANYL; FOLIC ACID; HOMOCYSTEINE; ISOFLURANE; NITROUS OXIDE; NITROUS OXIDE PLUS OXYGEN; PLACEBO; PROPOFOL; PYRIDOXINE; SUFENTANIL; VITAMIN B COMPLEX;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; ELECTIVE SURGERY; FEMALE; HEART MUSCLE ISCHEMIA; HIP ARTHROPLASTY; HUMAN; HYPERHOMOCYSTEINEMIA; INHALATION ANESTHESIA; KNEE ARTHROPLASTY; MALE; POSTOPERATIVE COMPLICATION; PREOPERATIVE TREATMENT; PRIORITY JOURNAL; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL;

EID: 0035193589     PISSN: 00032999     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000539-200112000-00034     Document Type: Article

References (19)

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9. Demonstration of rapid onset vascular endothelial dysfunction after hyperhomocysteinemia
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12. The use of intraoperative nitrous oxide leads to postoperative elevations in plasma homocysteine
13. Nitrous oxide-induced elevated homocysteine concentrations are associated with increased myocardial ischemia in patients undergoing carotid endarterectomy
14. What level of plasma homocyst(e)ine should be treated? Effects of vitamin therapy on progression of carotid atherosclerosis in patients with homocyst(e)ine levels above 14 μmol/L
15. GPOWER: A general power analysis program
16. General anesthetics
17. Vitamin requirements for the treatment of hyperhomocysteinemia in humans
18. Preoperative methionine loading enhances restoration of the cobalamin dependent enzyme methionine synthase after nitrous oxide anesthesia
19. Adverse vascular effects of homocysteine are modulated by endothelium-derived relaxing factor and related oxides of nitrogen