Antagonistic regulation of Dlx2 expression by PITX2 and Msx2: Implications for tooth development

Gene Expression

Volumn 9, Issue 6, 2001, Pages 265-281

  Green, P D ^a   Hjalt, T A ^b   Kirk, D E ^a   Sutherland, L B ^b   Thomas, B L ^c   Sharpe, P T ^c   Snead, M L ^d   Murray, J C ^b   Russo, A F ^b   Amendt, B A ^a  

^a UNIVERSITY OF TULSA   (United States)

^b UNIVERSITY OF IOWA   (United States)

^c KING'S COLLEGE LONDON   (United Kingdom)

^d UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

Dlx2; PITX2; Transcriptional regulation

Indexed keywords

BIOLOGICAL MARKER; HOMEODOMAIN PROTEIN; ISOPROTEIN; LUCIFERASE; PROTEIN DLX2; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR MSX2; TRANSCRIPTION FACTOR PITX2; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CHO CELL; CONTROLLED STUDY; DIMERIZATION; ELECTROPHORETIC MOBILITY; EPITHELIUM CELL; GENE EXPRESSION REGULATION; MOUSE; NONHUMAN; PROMOTER REGION; PROTEIN DNA BINDING; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM; REPORTER GENE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TOOTH DEVELOPMENT; TRANSCRIPTION REGULATION; WESTERN BLOTTING;

ANIMALIA;

EID: 0035192040     PISSN: 10522166     EISSN: None     Source Type: Journal    
DOI: 10.3727/000000001783992515     Document Type: Article

References (41)

1. Presence of negative and positive cis-acting RNA splicing elements within and flanking the first tat coding exon of the human immunodeficiency virus type 1
2. Rieger syndrome: A clinical, molecular and biochemical analysis
3. Presence of exon splicing silencers within human immunodeficiency virus type 1 tat exon 2 and tat-rev exon 3: Evidence for inhibition mediated by cellular factors
4. The molecular basis of Rieger syndrome: Analysis of Pitx2 homeodomain protein activities
5. Multifunctional role of the Pitx2 homeodomain protein C-terminal tail
6. Transcriptional antagonism between Hmx1 and Nkx2.5 for a shared DNA binding site
7. Maintenance of amelogenin gene expression by transformed epithelial cells of mouse enamel organ
8. The bicoid protein is a positive regulator of hunchback transcription in the early Drosophila embryo
9. The bicoid-related Pitx gene family in development
10. Dosage requirement of Pitx2 for development of multiple organs
11. Genetic analysis of the bicoid-related homeobox gene Pitx2
12. Homeodomain-DNA recognition
13. The Pitx2 protein in mouse development
14. Lef1 expression is activated by BMP-4 and regulates inductive tissue interactions in tooth and hair development
15. Biomineralization, life-time of odontogenic cells and differential expression of the two homeobox genes MSX-1 and DLX-2 in transgenic mice
16. Pitx2 regulates lung asymmetry, cardiac positioning and pituitary and tooth morphogenesis
17. Dlx genes encode DNA-binding proteins that are expressed in an overlapping and sequential pattern during basal ganglia differentiation
18. Function of Rieger syndrome gene in left-right asymmetry and craniofacial development
19. Expression patterns of the homeobox gene, Hox-8, in the mouse embryo suggest a role in specifying tooth initiation and shape
20. Expression of the transcription factors Otlx2, Barx1 and Sox9 during mouse odontogenesis
21. Mouse Otlx2/RIEG expression in the odontogenic epithelium precedes tooth initiation and requires mesenchyme-derived signals for its maintenance
22. Structure-function analysis of Msx2-mediated transcriptional suppression
23. Reciprocal regulation of osteocalcin transcription by the homeodomain proteins Msx2 and Dlx5
24. A graphical WWW-database on gene expression in tooth
25. The interaction with DNA of wild-type and mutant fushi tarazu homeodomains
26. Null mutation of Dlx-2 results in abnormal morphogenesis of proximal first and second branchial arch derivatives and abnormal differentiation in the forebrain
27. Differential and overlapping expression domains of Dlx-2 and Dlx-3 suggest distinct roles for Distal-less homeobox genes in craniofacial development
28. DNA binding and transcriptional properties of wild-type and mutant forms of the homeodomain protein MSX2
29. Spectrum and frequency of PITX2/RIEG mutations in patients with Rieger syndrome and related ocular anomalies
30. Cloning and characterization of a novel bicoid-related homeobox transcription factor gene, RIEG, involved in Rieger syndrome
31. Antagonistic signals between BMP4 and FGF8 define the expression of Pitx1 and Pitx2 in mouse tooth-forming anlage
32. Tooth morphogenesis and cell differentiation
33. Signalling networks regulating dental development
34. Independent regulation of Dlx2 expression in the epithelium and mesenchyme of the first branchial arch
35. The spatial localization of Dlx-2 during tooth development
36. Molecular control of odontogenic patterning: Positional dependent initiation and morphogenesis
37. Role of Dlx-1 and Dlx-2 genes in patterning of the murine dentition
38. Regulation of the calcitonin/calcitonin gene-related peptide gene by cell-specific synergy between helix-loop-helix and octamerbinding transcription factors
39. Identification of BMP-4 as a signal mediating secondary induction between epithelial and mesenchymal tissues during early tooth development
40. Conservation and diversification in homeodomain-DNA interactions: A comparative genetic analysis
41. Heterodimerization of Msx and Dlx homeoproteins results in functional antagonism