Influence of rifampicin pretreatment on the pharmacokinetics of tinidazole in healthy male volunteers

Clinical Drug Investigation

Volumn 21, Issue 11, 2001, Pages 783-787

  Alapati, V R ^a   Chaluvadi, M R ^a   Krishna, D R ^a  

^a KAKATIYA UNIVERSITY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450 2C9; CYTOCHROME P450 3A4; GLYCOPROTEIN P; RIFAMPICIN; TINIDAZOLE;

ADULT; AREA UNDER THE CURVE; ARTICLE; COMPUTER PROGRAM; DRUG ANTAGONISM; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DISTRIBUTION; DRUG ELIMINATION; DRUG HALF LIFE; DRUG INHIBITION; DRUG MECHANISM; DRUG METABOLISM; HUMAN; HUMAN EXPERIMENT; MALE; NORMAL HUMAN; PRIORITY JOURNAL; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

EID: 0035191730     PISSN: 11732563     EISSN: None     Source Type: Journal    
DOI: 10.2165/00044011-200121110-00006     Document Type: Article

References (10)

1. Tinidazole - Microbiology, pharmacology and efficacy in anaerobic infections
2. Rifampicin, a useful drug for nonmycobacterial infections
3. Clinically significant pharmacokinetic drug interactions with carbamazepine. An update
4. Cytochrome P450 isozymes and antiepileptic drug interactions
5. Effect of enzyme induction and inhibition on the fate of metronidazole and tinidazole in the rat
6. Orphan nuclear receptors CAR and PXR share xenobiotic and steroid ligands
7. The pharmacokinetics of metronidazole and tinidazole in man
8. Pharmacokinetics of tinidazole in male and female subjects
9. The role of intestinal P-glycoprotein in the interaction of digoxin and rifampicin
10. Drug interactions that matter: A critical reappraisal