Captopril restores transforming growth factor-β type II receptor and sensitivity to transforming growth factor-β in murine renal cell cancer cells

Journal of Urology

Volumn 165, Issue 2, 2001, Pages 616-620

  Miyajima, Akira ^a   Asano, Tomohiko ^a   Hayakawa, Masamichi ^a  

^a NATIONAL DEFENSE MEDICAL COLLEGE   (Japan)

Author keywords

Captopril; Carcinoma; Kidney; Mice; Receptors; Renal cell; Transforming growth factor beta

Indexed keywords

BROXURIDINE; CAPTOPRIL; MESSENGER RNA; TETRAZOLIUM; TRANSFORMING GROWTH FACTOR BETA RECEPTOR; TRANSFORMING GROWTH FACTOR BETA2;

ANIMAL CELL; ARTICLE; CANCER INHIBITION; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; FLOW CYTOMETRY; KIDNEY CARCINOMA; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR SENSITIVITY; RECEPTOR UPREGULATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUMOR CELL CULTURE;

EID: 0035190076     PISSN: 00225347     EISSN: None     Source Type: Journal    
DOI: 10.1097/00005392-200102000-00083     Document Type: Article

References (13)

1. Captopril inhibits angiogenesis and slows the growth of experimental tumors in rats
2. An assay for transforming growth factor-beta using cells transfected with a plasminogen activator inhibitor-promoter-luciferase construct
3. Inactivation of the type II TGF-β receptor in colon cancer cells with microsatellite instability
4. Down-regulation of protein and mRNA expression for transforming growth factor-β type I and type II receptors in human prostate cancer
5. Loss of expression of transforming growth factor-β receptors is associated with poor prognosis in prostate cancer patients
6. Overexpression of transforming growth factor-β1 type II receptor restores TGF-β1 sensitivity and signaling in human prostate cancer cells
7. Expression of transforming growth factor-β type II receptor reduces tumorigenicity in human gastric cancer cells
8. Transforming growth factor-beta type II receptor confers tumor suppressor activity in murine renal carcinoma (Renca) cells
9. Regulation of transforming growth factor-β type II receptor expression in human breast cancer MCF-7 cells by Vitamin D3 and its analogue
10. Differentiation and cell surface expression of transforming growth factor-β receptors are regulated by interaction with matrix collagen in murine osteoblastic cells
11. Abnormal regulation of transforming growth factor-β receptors on vascular smooth muscle cells from spontaneously hypertensive rats by angiotensin II
12. Captopril reverses high-glucose growth effects on LLC-PK1 cells partly by decreasing transforming growth factor-β receptor protein expressions
13. Link between angiotensin II and TGF-β in the kidney