Serum and WBC pharmacokinetics of 1500 mg of azithromycin when given either as a single dose or over a 3 day period in healthy volunteers

Journal of Antimicrobial Chemotherapy

Volumn 47, Issue 1, 2001, Pages 61-66

  Amsden, Guy W ^a,b   Gray, Clare L ^b  

^a BASSETT RESEARCH INSTITUTE   (United States)

^b BASSETT HEALTHCARE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AZITHROMYCIN;

ADULT; AREA UNDER THE CURVE; ARTICLE; BLOOD SAMPLING; CLINICAL TRIAL; COMPARTMENT MODEL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DRUG BLOOD LEVEL; DRUG EXPOSURE; FEMALE; GASTROINTESTINAL SYMPTOM; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HOT FLUSH; HUMAN; HUMAN EXPERIMENT; LEUKOCYTE; LIQUID CHROMATOGRAPHY; LYMPHOCYTE; MALE; MASS SPECTROMETRY; MONOCYTE; NAUSEA; NEUTROPHIL; NORMAL HUMAN; RANDOMIZED CONTROLLED TRIAL; RESPIRATORY TRACT INFECTION; VOLUNTEER;

EID: 0035182256     PISSN: 03057453     EISSN: None     Source Type: Journal    
DOI: 10.1093/jac/47.1.61     Document Type: Article

References (13)

1. Azithromycin. A review of its pharmacological properties and use as a 3-day therapy in respiratory tract infections
2. Pharmacokinetics in serum and leukocyte exposures of oral azithromycin, 1500 mg, given over a 3- or 5-day period in healthy subjects
3. Comparison of the pharmacokinetics of three-day and five-day-regimens of azithromycin in plasma and urine
4. Azithromycin: The first azalide antibiotic
5. Randomised controlled trial of single-dose azithromycin in treatment of trachoma
6. Azithromycin: Single 1.5 g dose in the treatment of patients with atypical pneumonia syndrome - A randomized study
7. TopFit: A PC-based pharmacokinetic/pharmacodynamic data analysis program
8. Mean cell volume of human blood leukocytes and resident and activated murine macrophages
9. The role of advanced generation macrolides in the prophylaxis and treatment of Mycobacterium avium complex (MAC) infections
10. The absence of an effect of food on the bioavailability of azithromycin administered as tablets, sachet or suspension
11. Postantibiotic effects and the dosing of macrolides, azalides and streptogramins
12. Pneumococcal macrolide resistance-myth or reality?
13. Single-dose azithromycin vs ceftriaxone for treatment of uncomplicated gonorrhea