Immunohistochemical localization of membrane type 1-matrix metalloproteinase (MT1-MMP) in osteoclasts in vivo

Tissue and Cell

Volumn 33, Issue 5, 2001, Pages 478-482

  Irie,, K ^a   Tsuruga,, E ^a   Sakakura,, Y ^a   Muto,, T ^a   Yajima, T ^a  

^a HEALTH SCIENCES UNIVERSITY OF HOKKAIDO   (Japan)

Author keywords

Bone resorption; Immunohistochemistry; MT1 MMP; Osteoclast

Indexed keywords

GOLD DERIVATIVE; HORSERADISH PEROXIDASE; INTERSTITIAL COLLAGENASE; MATRIX METALLOPROTEINASE INHIBITOR;

ANIMAL CELL; ARTICLE; BONE TURNOVER; CELL MEMBRANE; CELL MIGRATION; CELL SURFACE; CELL ULTRASTRUCTURE; CELL VACUOLE; CYTOPLASM; ENZYME ACTIVITY; ENZYME LOCALIZATION; EXTRACELLULAR MATRIX; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; OSTEOCLAST; OSTEOLYSIS; PROTEIN DEGRADATION; RAT; REGULATORY MECHANISM;

EID: 0035181911     PISSN: 00408166     EISSN: None     Source Type: Journal    
DOI: 10.1054/tice.2001.0201     Document Type: Article

References (24)

1. Osteoclastic bone resorption by a polarized vacuolar proton pump
2. Matrix metalloproteinases are obligatory for the migration of preosteoclasts to the developing marrow cavity of primitive long bones
3. Resorption of dentine by isolated osteoclasts in vitro
4. Resorption of bone by isolated rabbit osteoclasts
5. The expression of metalloproteinase-2, -9, and -14 and of tissue inhibitors-1 and -2 is developmentally odulated during osteogenesis in vitro, the mature osteoblastic phenotype expressing metalloproteinase-14
6. Activation of human umbilical vein endothelial cell progelatinase A by phorbol myristate acetate: A protein kinase C-dependent mechanism involving a membrane-type matrix metalloproteinase
7. Pycnodysostosis, a lysosomal disease caused by cathepsin K deficiency
8. MT1-MMP-deficient mice develop dwarfism, osteopenia, arthritis, and connective tissue disease due to inadequate collagen turnover
9. Plasma membrane-dependent activation of gelatinase A in human vascular endothelial cells
10. Cell-substratum interaction of cultured avian osteoclasts is mediated by specific adhesion structures
11. Transmembrane/cytoplasmic domain-mediated membrane type 1-matrix metalloprotease docking to invadopodia is required for cell invasion
12. (+)-ATPase in osteoclasts of rat tibiae
13. Localization of matrix metalloproteinase 9 (92-kilodalton gelatinase/type IV collagenase = gelatinase B) in osteoclasts: Implications for bone resorption
14. A matrix metalloproteinase expressed on the surface of invasive tumour cells
15. Identification of the membrane-type matrix metalloproteinase MT1-MMP in osteoclasts
16. Membrane-type matrix metalloproteinases
17. Clear zone in osteoclast function: Role of podosomes in regulation of bone-resorbing activity
18. Identification of matrix metalloproteinase 9 in rabbit osteoclasts
19. Molecular cloning of a possible cysteine proteinase predominantly expressed in osteoclasts
20. Adhesion patterns and cytoskeleton of rabbit osteoclasts on bone slices and glass
21. Immunocytochemical and immunochemical detection of a 32 kDa nonamelogenin and related proteins in porcine tooth germs
22. mRNA expression of MT1-MMP, MMP-9, cathepsin K, and TRAP in highly enriched osteoclasts cultured on several matrix proteins and ivory surfaces
23. (+)-ATPase type in the ruffled borders of osteoclasts
24. Study of immunoelectron microscopic localization of cathepsin K in osteoclasts and other bone cells in the mouse femur