The role of high-density lipoproteins in oxidation and inflammation

Trends in Cardiovascular Medicine

Volumn 11, Issue 3-4, 2001, Pages 155-161

  Van Lenten, Brian J ^a,b   Navab, Mohamad ^a   Shih, Diana ^a   Fogelman, Alan M ^a   Lusis, Aldons J ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 ALKYL 2 ACETYLGLYCEROPHOSPHOCHOLINE ESTERASE; APOLIPOPROTEIN A1; APOLIPOPROTEIN A2; ARYLDIALKYLPHOSPHATASE; CERULOPLASMIN; CLUSTERIN; HIGH DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN; OXIDIZED LOW DENSITY LIPOPROTEIN; SERUM AMYLOID A; THROMBOCYTE ACTIVATING FACTOR;

ANTIINFLAMMATORY ACTIVITY; ATHEROGENESIS; HUMAN; INFLAMMATION; LIPID COMPOSITION; LIPID OXIDATION; LIPOPROTEIN METABOLISM; NONHUMAN; PRIORITY JOURNAL; REGULATORY MECHANISM; REVIEW;

ANIMALS; HUMANS; INFLAMMATION; INFLAMMATION MEDIATORS; LIPID PEROXIDATION; LIPOPROTEINS, HDL;

EID: 0035181877     PISSN: 10501738     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1050-1738(01)00095-0     Document Type: Review

References (49)

1. The inhibition of lipid autoxidation by human ceruloplasmin
2. Apolipoprotein J expression at fluid-tissue interfaces: Potential role in barrier cytoprotection
3. Paraoxonase active site required for protection against LDL oxidation involves its free sulfhydryl group and is different from that required for its arylesterase/paraoxonase activities
4. Human serum paraoxonase (PON1) Q and R selectively decrease lipid peroxides in human coronary and carotid atherosclerotic lesions
5. Paraoxonase inhibits high-density lipoprotein oxidation and preserves its functions
6. Serum amyloid A (SAA): Influence on HDL-mediated cellular cholesterol efflux
7. Hepatic apolipoprotein J is secreted as a lipoprotein
8. Zinc, copper and ceruloplasmin in arteriosclerosis
9. Effects of the acute phase response on the concentration and density distribution of plasma lipids and apolipoproteins
10. Overexpression of apolipoprotein AII in transgenic mice converts high density lipoproteins to proinflammatory particles
11. The effect of the human serum paraoxonase polymorphism is reversed with diazoxon, soman and sarin
12. Intact human ceruloplasmin oxidatively modifies low density lipoprotein
13. Targeted disruption of the murine lecithin: Cholesterol acyltransferase gene is associated with reductions in plasma paraoxonase and platelet-activating factor acetylhydrolase activities but not in apolipoprotein J concentration
14. Human clusterin gene expression is confined to surviving cells during in vitro programmed cell death
15. Ceruloplasmin. A scavenger of superoxide anion radicals
16. Cerulolasmin: Physiological and pathological perspectives
17. Endotoxin and cytokines decrease serum levels and extra hepatic protein and mRNA levels of cholesteryl ester transfer protein in syrian hamsters
18. Mouse apolipoprotein J: Characterization of a gene implicated in atherosclerosis
19. Apolipoprotein J is associated with paraoxonase in human plasma
20. Acidic pH enables ceruloplasmin to catalyze the modification of low density lipoprotein
21. Hydrolysis and transesterification of platelet-activating factor by lecithin-cholesterol acyltransferase
22. Paraoxonase prevents accumulation of lipoperoxides in low-density lipoprotein
23. Alloenzymes of paraoxonase and effectiveness of high-density lipoproteins in protecting low-density lipoprotein against lipid peroxidation
24. Effect of the human serum paraoxonase 55 and 192 genetic polymorphisms on the protection by high density lipoprotein against low density lipoprotein oxidative modification
25. Paraoxonase and coronary heart disease
26. Normal HDL inhibits three steps in the formation of mildly oxidized LDL: Step 1
27. Normal HDL inhibits three steps in the formation of mildly oxidized LDL: Steps 2 & 3
28. Mildly oxidized LDL induces an increased apolipoprotein J/paraoxonase ratio
29. Monocyte transmigration induced by modification of LDL in cocultures of human aortic wall cells is due to induction of MCP 1 synthesis and is abolished by HDL
30. Acute phase proteins with special reference to C-reactive protein and related proteins (pentaxins) and serum amyloid A protein
31. Genes influencing HDL metabolism: New perspectives and implications for atherosclerosis prevention
32. Clusterin: Physiologic and pathophysiologic considerations
33. Inhibition of superoxide and ferritin-dependent lipid peroxidation by ceruloplasmin
34. Genetic-dietary regulation of serum paraoxonase expression and its role in atherogenesis in a mouse model
35. Mice lacking serum paraoxonase are susceptible to organophosphate toxicity and atherosclerosis
36. Combined serum paraoxonase knockout/apolipoprotein E knockout mice exhibit increased lipoprotein oxidation and atherosclerosis
37. Mammalian platelet-activating factor acetylhydrolases
38. Platelet-activating factor acetylhydrolase deficiency. A missense mutation near the active site of an anti-inflammatory phospholipase
39. Role of lecithin-cholesterol acyltransferase in the metabolism of oxidized phospholipids in plasma: Studies with platelet-activating factor-acetyl hydrolase-deficient plasma
40. Anti-inflammatory properties of a platelet-activating factor acetylhydrolase
41. Clusterin: Modulation of complement function
42. Anti-inflammatory HDL becomes pro-inflammatory during the acute phase response. Loss of protective effect of HDL against LDL oxidation in aortic wall cell cocultures
43. Platelet-activating factor: A phospholipid autacoid with diverse actions
44. Atherosclerosis in transgenic mice overexpressing apolipoprotein A-II
45. Protective effect of high density lipoprotein associated paraoxonase. Inhibition of the biological activity of minimally oxidized low density lipoprotein
46. Structural identification by mass spectrometry of oxidized phospholipids in minimally oxidized low density lipoprotein that induce monocyte/endothelial interactions and evidence for their presence in vivo
47. Effect of platelet activating factor-acetylhydrolase on the formation and action of minimally oxidized low density lipoprotein
48. Correlations between plasma platelet-activating factor acetylhydrolase (PAF-AH) activity and PAF-AH genotype, age, and atherosclerosis in a Japanese population
49. Major acute-phase reactant synthesis during chronic inflammation in amyloid-susceptible and -resistant mouse strains