Increase in spontaneous action potentials and sensitivity in response to norepinephrine in dorsal root ganglion neurons of adjuvant inflamed rats

Neuroscience Research

Volumn 39, Issue 1, 2001, Pages 109-113

  Kasai, Masanori ^a,b   Mizumura, Kazue ^a  

^a NAGOYA UNIVERSITY   (Japan)

^b KAGOSHIMA UNIVERSITY   (Japan)

Author keywords

Adjuvant inflammation; Dorsal root ganglion neuron; Intracellular recording; Nerve growth factor; Norepinephrine; Spontaneous activity

Indexed keywords

ADJUVANT; NERVE GROWTH FACTOR; NORADRENALIN;

ACTION POTENTIAL; ANIMAL CELL; ARTICLE; CELL CULTURE; CONTROLLED STUDY; DRUG SENSITIVITY; HYPERALGESIA; IN VITRO STUDY; INFLAMMATION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SPINAL GANGLION;

ACTION POTENTIALS; ADRENERGIC ALPHA-AGONISTS; ANIMALS; FREUND'S ADJUVANT; GANGLIA, SPINAL; MALE; NERVE GROWTH FACTOR; NEURONS; NOREPINEPHRINE; RATS; RATS, WISTAR;

EID: 0035173455     PISSN: 01680102     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-0102(00)00201-7     Document Type: Review

References (20)

1. Effects of nerve growth factor on TTX-and capsaicin-sensitivity in adult rat sensory neurons
2. + channel III and SNS gene expression in spinal sensory neurons
3. Differential role of GDNF and NGF in the maintenance of two TTX-resistant sodium channels in adult DRG neurons
4. Rapid sodium channel augmentation in response to inflammation induced by complete Freund's adjuvant
5. A role for nerve growth factor in sympathetic sprouting in rat dorsal root ganglia
6. Nerve growth factor sustains the response to capsaicin in cultured neurones from adult rat dorsal root ganglia
7. Increased incidence of dorsal root ganglion neurons with spontaneous activity and the responses to bradykinin and capsaicin in adjuvant arthritic rats
8. Nerve growth factor increases sensitivity to bradykinin, mediated through B2 receptors, in capsaicin-sensitive small neurons cultured from rat dorsal root ganglia
9. Endogenous nerve growth factor increases the sensitivity to bradykinin in small dorsal root ganglion neurons of adjuvant inflamed rats
10. Neutralization of endogenous NGF prevents the sensitization of nociceptors supplying inflamed skin
11. Noradrenaline hyperalgesia is mediated through interaction with sympathetic postganglionic neurone terminals rather than activation of primary afferent nociceptors
12. Effects of paracetamol and aspirin on neuronal activity of joint mechanonociceptors in adjuvant arthritis
13. Bradykinin B-1 and B-2 receptor antagonists do not change the ongoing activity of slowly conducting articular afferents in the inflamed knee joint of the cat
14. Abnormal spontaneous activity and responses to norepinephrine in dissociated dorsal root ganglion cells after chronic nerve constriction
15. Adrenergic excitation of cutaneous nociceptors in chronically inflamed rats
16. Norepinephrine excitation of cutaneous nociceptors in adjuvant-induced inflamed rats does not depend on sympathetic neurons
17. + channel expression increases in dorsal root ganglion neurons in the carrageenan inflammatory pain model
18. Functional changes in dorsal root ganglion cells after chronic nerve constriction in the rat