High-level, but not low-level, occupational exposure to inhaled anesthetics is associated with genotoxicity in the micronucleus assay

Anesthesia and Analgesia

Volumn 92, Issue 1, 2001, Pages 118-122

  Wiesner, Gunther ^a   Hoerauf, Klaus ^b   Schroegendorfer, Klaus ^b   Sobczynski, Pawel ^c   Harth, Marion ^a   Ruediger, Hugo W ^b  

^a UNIVERSITY OF REGENSBURG   (Germany)

^b UNIVERSITY OF VIENNA   (Austria)

^c ADAM MICKIEWICZ UNIVERSITY   (Poland)

Author keywords

[No Author keywords available]

Indexed keywords

INHALATION ANESTHETIC AGENT; NITROUS OXIDE;

ADULT; ANESTHESIST; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GENOTOXICITY; HOSPITAL DEPARTMENT; HUMAN; MALE; MICRONUCLEUS TEST; OCCUPATIONAL EXPOSURE; OCCUPATIONAL SAFETY; OCCUPATIONAL TOXICOLOGY; PRIORITY JOURNAL; RISK ASSESSMENT;

EID: 0035172678     PISSN: 00032999     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000539-200101000-00023     Document Type: Article

References (25)

1. Anesthesia, pregnancy, and miscarriage: A study of operating room nurses and anesthetists
2. Occupational disease in dentistry and chronic exposure to trace anesthetic gases
3. Health effects associated with exposure to anaesthetic gases in Ontario hospital personnel
4. Reduced fertility among women employed as dental assistants exposed to high levels of nitrous oxide
5. Nitrous oxide and spontaneous abortion in female dental assistants
6. The cytokinesis-block micronucleus technique: A detailed description of the method and its application to genotoxicity studies in human populations
7. Occupational exposure to inhaled anaesthetics: A follow-up study on anaesthetists of an eastern European university hospital
8. Occupational exposure to sevoflurane and nitrous oxide in operating room personnel
9. Waste gas exposure during desflurane and isoflurane anaesthesia
10. Sample size and power
11. Chromosome aberrations, micronuclei, aneuploidy, sister chromatid exchanges, and cancer risk assessment
12. Increased micronucleus formation in nurses with occupational nitrous oxide exposure in operating theaters
13. Genetic damage in operating room personnel exposed to isoflurane and nitrous oxide
14. Cytogenetic damage in operation theatre personnel
15. Chromosome and sister-chromatid exchange analysis in peripheral lymphocytes, and mutagenicity of urine in anesthesiology personnel
16. Sister-chromatid exchanges in operating room personnel
17. Waste anaesthetic gases induce sister chromatid exchanges in lymphocytes of operating room personnel
18. Chromosomal aberrations in lymphocytes predict human cancer: A report from the European Study Group on Cytogenetic Biomarkers and Health (ESCH)
19. Comparison between micronucleated lymphocyte rates observed in healthy subjects and cancer patients
20. Micronuclei in cytokinesis-blocked lymphocytes as an index of occupational exposure to alkylating cytostatic drugs
21. Human lymphocytes micronucleus assay in Europe: An international survey
22. The human lymphocyte micronucleus assay: A comparison between whole blood and separated-lymphocyte cultures
23. Important variables that influence base-line micronucleus frequency in cytokinesis-blocked lymphocytes: A biomarker for DNA damage in human populations
24. Metabolism and toxicity of inhaled anesthetics