Expression of interleukin-6, interleukin-6 receptor (gp80), and the receptor's signal-transducing subunit (gp130) in human normal pituitary glands and pituitary adenomas

Modern Pathology

Volumn 14, Issue 8, 2001, Pages 791-797

  Kurotani, Reiko ^a   Yasuda, Masanori ^a   Oyama, Kenichi ^b   Egashira, Noboru ^a   Sugaya, Muthumi ^a   Teramoto, Akira ^b   Osamura, R Yoshiyuki ^a  

^a TOKAI UNIVERSITY   (Japan)

^b NIPPON MEDICAL SCHOOL   (Japan)

Author keywords

Gp130; Gp80; Human pituitary adenoma; Human pituitary gland; IL 6; Immunohistochemistry

Indexed keywords

CORTICOTROPIN; FOLLITROPIN; GLYCOPROTEIN GP 130; INTERLEUKIN 6; INTERLEUKIN 6 RECEPTOR; LUTEINIZING HORMONE; RECEPTOR SUBUNIT;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; CORTICOTROPIN RELEASE; FEMALE; GENE EXPRESSION; GONADOTROPIN SECRETING CELL; GROWTH HORMONE RELEASE; HUMAN; HUMAN TISSUE; HYPOPHYSIS; HYPOPHYSIS ADENOMA; HYPOPHYSIS CELL; IMMUNOHISTOCHEMISTRY; MALE; PRIORITY JOURNAL; PROLACTIN SECRETING CELL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ADENOMA; AGED; AGED, 80 AND OVER; ANTIGENS, CD; CYTOKINE RECEPTOR GP130; FEMALE; GENE EXPRESSION REGULATION; HUMANS; IMMUNOHISTOCHEMISTRY; INTERLEUKIN-6; MALE; MEMBRANE GLYCOPROTEINS; MIDDLE AGED; PITUITARY GLAND; PITUITARY HORMONES; PITUITARY NEOPLASMS; RECEPTORS, INTERLEUKIN-6; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; S100 PROTEINS;

EID: 0035170803     PISSN: 08933952     EISSN: None     Source Type: Journal    
DOI: 10.1038/modpathol.3880392     Document Type: Article

References (23)

1. Changes in plasma IL-1beta, TNF-alpha and IL-6 after total hip replacement surgery in general or regional anaesthesia
2. Immune-neuro-endocrine interactions: Facts and hypotheses
3. Interleukin-6 in biology and medicine
4. Interleukin-6: An overview
5. IL-6 type cytokine receptor complexes: Hexamer, tetramer or both?
6. Interleukin-6-type cytokine signalling through the gp130/Jak/STAT pathway
7. Interleukin-6 transduction of a rat T9 glioma clone results in attenuated tumorigenicity and induces glioma immunity in Fischer F344 rats
8. The importance of IL-6 protein expression in primary human renal cell carcinoma: An immunohistochemical study
9. Role of interleukin-6 in the pathogenesis of multiple myeloma
10. Interleukin-6 stimulates anterior pituitary hormone release in vitro
11. Effects of recombinant human interleukin-1 alpha, -1 beta, 2 and 6 on ACTH synthesis and release in the mouse pituitary tumour cell line AtT-20
12. Production of bioactive and immunoreactive interleukin-6 (IL-6) and expression of IL-6 messenger ribonucleic acid by human pituitary adenomas
13. Expression of IL-6 mRNA in normal rat and human pituitaries and in human pituitary adenomas
14. Biologic markers of invasive pituitary adenomas involving the sphenoid sinus
15. The structure and function of folliculo-stellate cells in the anterior pituitary gland
16. Pituitary folliculo-stellate-like cell line produces a cytokine-induced neutrophil chemoattractant
17. Interleukin-6 and the interleukin-6 receptor in the human adrenal gland: Expression and effects on steroidogenesis
18. The function of the soluble IL-6 receptor in vivo
19. Interleukin-6 secreting human pituitary adenomas in vitro
20. Interleukin-6 and interleukin-6 receptor gene expression in pituitary tumors
21. Heterogeneity of pituitary folliculo-stellate cells: Implications for interleukin-6 production and accessory function in vitro
22. Strenuous resistive breathing induces proinflammatory cytokines and stimulates the HPA axis in humans
23. Molecular mechanisms of actions of interleukin-6 on the brain, with special reference to serotonin and the hypothalamo-pituitary-adrenocortical axis