Enhancement of protein activity in a recombinant fermentation by optimizing fluid dispersion and initial plasmid copy number distribution

Biochemical Engineering Journal

Volumn 9, Issue 2, 2001, Pages 111-118

  Patnaik, P R ^a  

^a INSTITUTE OF MICROBIAL TECHNOLOGY   (India)

Author keywords

Fluid dispersion; GAPDH activity; Plasmid copy number distribution; Recombinant fermentation

Indexed keywords

GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE;

ARTICLE; BIOREACTOR; CELL POPULATION; DISPERSION; ESCHERICHIA COLI; FERMENTATION; MATHEMATICAL ANALYSIS; NONHUMAN; PLASMID; PRIORITY JOURNAL;

EID: 0035170515     PISSN: 1369703X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1369-703X(01)00130-9     Document Type: Article

References (20)

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5. Influence of macromixing on plasmid stability during batch fermentation with recombinant bacteria
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7. The kinetics of plasmid loss
8. Optimizing initial plasmid copy number distribution for improved protein activity in a recombinant fermentation
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18. Effect of cycling on the stability of plasmid-bearing organisms in continuous culture