Equivalent parental distribution of frequently lost alleles and biallelic expression of the H19 gene in human testicular germ cell tumors

Japanese Journal of Cancer Research

Volumn 87, Issue 8, 1996, Pages 816-823

  Mishina, Mutsuki ^a   Ogawa, Osamu ^a   Kinoshita, Hidefumi ^a   Oka, Hiroya ^a   Okumura, Kazuhiro ^a   Mitsumori, Kenji ^a   Kakehi, Yoshiyuki ^a   Reeve, Anthony E ^b   Yoshida, Osamu ^a  

^a KYOTO UNIVERSITY   (Japan)

^b UNIVERSITY OF OTAGO   (New Zealand)

Author keywords

H19; Imprinting; Loss of heterozygosity; Parental origin; Testicular germ cell tumor

Indexed keywords

ADULT; ALLELE; ARTICLE; CHILD; CHROMOSOME 11P; CHROMOSOME 17P; CHROMOSOME 1P; CHROMOSOME 3P; CLINICAL ARTICLE; CONTROLLED STUDY; GENE EXPRESSION; GENE LOSS; GENOME IMPRINTING; GERM CELL TUMOR; HETEROZYGOSITY LOSS; HUMAN; HUMAN TISSUE; MALE; PRESCHOOL CHILD; PRIORITY JOURNAL; TESTIS TUMOR; TUMOR SUPPRESSOR GENE;

EID: 0029788882     PISSN: 09105050     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1349-7006.1996.tb02105.x     Document Type: Article

References (36)

1. Fearon, E. R. and Vogelstein, B. A genetic model for colorectal tumorigenesis. Cell, 61, 759-767 (1990).
2. Feinberg, A. P. and Vogelstein, B. Hypermethylation distinguishes genes of some human cancers from their normal counterparts. Nature, 301, 89-92 (1983).
3. Sakai, T., Toguchida, J., Ohtani, N., Yandell, D. W., Rapaport, J. M. and Dryja, T. P. Allele-specific hypermethylation of the retinoblastoma tumor-suppressor gene. Am. J. Hum. Genet., 48, 880-888 (1991).
4. Herman, J. G., Latif, F., Weng, Y., Lerman, M. I., Zbar, B., Liu, S., Samid, D., Duan, D. S. R., Gnarra, J. R., Linehan, W. M. and Baylin, S. B. Silencing of the VHL tumor-suppressor gene by DNA methylation in renal carcinoma. Proc. Natl. Acad. Sci. USA, 91, 9700-9704 (1994).
5. Merlo, A., Herman, J. G., Mao, L., Lee, D. J., Gabrielson, E., Burger, P. C., Baylin, S. B. and Sidransky, D. 5′ CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers. Nat. Med., 1, 686-692 (1995).
6. Rainier, S. and Feinberg, A. P. Genomic imprinting, DNA methylation, and cancer. J. Natl. Cancer Inst., 86, 753-759 (1994).
7. Solter, D. Inertia of the embryonic genome in mammals. Trends Genet., 3, 23-27 (1987).
8. Schroeder, W. T., Chao, L. Y., Dao, D. D., Strong, L. C., Pathak, S., Riccardi, V., Lewis, W. H. and Saunders, G. F. Nonrandom loss of maternal chromosome 11 alleles in Wilms tumors. Am. J. Hum. Genet., 40, 413-420 (1987).
9. Scrable, H., Cavenee, W., Ghavimi, F., Lovell, M., Morgan, K. and Sapienza, C. A model for embryonal rhabdomyosarcoma tumorigenesis that involves genome imprinting. Proc. Natl. Acad. Sci. USA, 86, 7480-7484 (1989).
10. Toguchida, J., Ishizaki, K., Sasaki, M. S., Nakamura, Y., Ikenaga, M., Kato, M., Sugimoto, M., Kotoura, Y. and Yamamuro, T. Preferential mutation of paternally derived RB gene as the initial event in sporadic osteosarcoma. Nature, 338, 156-158 (1989).
11. Ogawa, O., Eccles, M. R., Szeto, J., McNoe, L. A., Yun, K., Maw, M. A., Smith, P. J. and Reeve, A. E. Relaxation of insulin-like growth factor II gene imprinting implicated in Wilms' tumour. Nature, 362, 749-751 (1993).
12. Zhan, S., Shapiro, D. N. and Helman, L. J. Activation of an imprinted allele of the insulin-like growth factor II gene implicated in rhabdomyosarcoma. J. Clin. Invest., 94, 445-448 (1994).
13. Rainier, S., Dobry, C. J. and Feinberg, A. P. Loss of imprinting in hepatoblastoma. Cancer Res., 55, 1836-1838 (1995).
14. Hashimoto, K., Azuma, C., Koyama, M., Ohashi, K., Kamiura, S., Nobunaga, T., Kimura, T., Tokugawa, Y., Kanai, T. and Saji, F. Loss of imprinting in choriocarcinoma. Nat. Genet., 9, 109-110 (1995).
15. Kondo, M., Suzuki, H., Ueda, R., Osada, H., Takagi, K., Takahashi, T. and Takahashi, T. Frequent loss of imprinting of the H19 gene is often associated with its overexpression in human lung cancers. Oncogene, 10, 1193-1198 (1995).
16. de Jong, B., Oosterhuis, J. W., Castedo, S. M. M. J., Vos, A. and te Meerman, G. J. Pathogenesis of adult testicular germ cell tumors. A cytogenetic model. Cancer Genet. Cytogenet., 48, 143-167 (1990).
17. Bosl, G. J., Dmitrovsky, E., Reuter, V. E., Samaniego, F., Rodriguez, E., Geller, N. L. and Chaganti, R. S. K. Isochromosome of chromosome 12: clinically useful marker for male germ cell tumors. J. Natl. Cancer Inst., 81, 1874-1878 (1989).
18. Castedo, S. M. M. J., de Jong, B., Oosterhuis, J. W., Seruca, R., te Meerman, G. J., Dam, A. and Koops, H. S. Cytogenetic analysis of ten human seminomas. Cancer Res., 49, 439-443 (1989).
19. Lothe, R. A., Hastie, N., Heimdal, K., Fosså, S. D., Stenwig, A. E. and Børresen, A. L. Frequent loss of 11p13 and 11p15 loci in male germ cell tumours. Genes Chrom. Cancer, 7, 96-101 (1993).
20. Looijenga, L. H. J., Abraham, M., Gillis, A. J. M., Saunders, G. F. and Oosterhuis, J. W. Testicular germ cell tumors of adults show deletions of chromosomal bands 11p13 and 11p15.5, but no abnormalities within the zincfinger regions and exons 2 and 6 of the Wilms' tumor I gene. Genes Chrom. Cancer, 9, 153-160 (1994).
21. Murty, V. V. V. S., Bosl, G. J., Houldsworth, J., Meyers, M., Mukherjee, A. B., Reuter, V. and Chaganti, R. S. K. Allelic loss and somatic differentiation in human male germ cell tumors. Oncogene, 9, 2245-2251 (1994).
22. Mostofi, F. K. and Sobin, L. H. "Histological Typing of Testis Tumours," International Histological Classification of Tumours, Vol. 16 (1977) WHO, Geneva.
23. International Union against Cancer (UICC). "TNM Classification of Malignant Tumours," 3rd Ed., pp. 227-236 (1989). Springer-Verlag, Berlin.
24. Ogawa, O., Kakehi, Y., Ogawa, K., Koshiba, M., Sugiyama, T. and Yoshida, O. Allelic loss at chromosome 3p characterizes clear cell phenotype of renal cell carcinoma. Cancer Res., 51, 949-953 (1991).
25. Peng, H. Q., Hogg, D., Malkin, D., Bailey, D., Gallie, B. L., Bulbul, M., Jewett, M., Buchanan, J. and Goss, P. E. Mutations of the p53 gene do not occur in testis cancer. Cancer Res., 53, 3574-3578 (1993).
26. Ganguly, S., Murty, V. V. V. S., Samaniego, F., Reuter, V. E., Bosl, G. J. and Chaganti, R. S. K. Detection of preferential NRAS mutations in human male germ cell tumors by polymerase chain reaction. Genes Chrom. Cancer, 1, 228-232 (1990).
27. Kajii, T. and Ohama, K. Androgenetic origin of hydatidiform mole. Nature, 268, 633-634 (1977).
28. Linder, D., McCaw, B. K. and Hecht, F. Parthenogenic origin of benign ovarian teratomas. N. Engl. J. Med., 292, 63-66 (1975).
29. Szabó, P. E. and Mann, J. R. Biallelic expression of imprinted genes in the mouse germ line: implications for erasure, establishment, and mechanisms of genomic imprinting. Genes Dev., 9, 1857-1868 (1995).
30. Walsh, C., Miller, S. J., Flam, F., Fisher, R. A. and Ohlsson, R. Paternally derived H19 is differentially expressed in malignant and nonmalignant trophoblast. Cancer Res., 55, 1111-1116 (1995).
31. van Gurp, R. J. H. L. M., Oosterhuis, J. W., Kalscheuer, V., Mariman, E. C. M. and Looijenga, L. H. J. Biallelic expression of the H19 and IGF2 genes in human testicular germ cell tumors. J. Natl. Cancer Inst., 86, 1070-1075 (1994).
32. Hao, Y., Crenshaw, T., Moulton, T., Newcomb, E. and Tycko, B. Tumor-suppressor activity of H19 RNA. Nature, 365, 764-766 (1993).
33. Zhang, Y., Shields, T., Crenshaw, T., Hao, Y., Moulton, T. and Tycko, B. Imprinting of human H19 : allele-specific CpG methylation, loss of the active allele in Wilms tumor, and potential for somatic allele switching. Am. J. Hum. Genet., 53, 113-124 (1993).
34. Steenman, M. J. C., Rainier, S., Dobry, C. J., Grundy, P., Horon, I. L. and Feinberg, A. P. Loss of imprinting of IGF2 is linked to reduced expression and abnormal methylation of H19 in Wilms' tumour. Nat. Genet., 7, 433-439 (1994).
35. Moulton, T., Crenshaw, T., Hao, Y., Moosikasuwan, J., Lin, N., Dembitzer, F., Hensle, T., Weiss, L., McMorrow, L., Loew, T., Kraus, W., Gerald, W. and Tycko, B. Epigenetic lesions at the H19 locus in Wilms' tumour patients. Nat. Genet., 7, 440-447 (1994).
36. Taniguchi, T., Sullivan, M. J., Ogawa, O. and Reeve, A. E. Epigenetic changes encompassing the IGF2/H19 locus associated with relaxation of IGF2 imprinting and silencing of H19 in Wilms tumor. Proc. Natl. Acad. Sci. USA, 92, 2159-2163 (1995).