The unique tryptophan residue of the vitamin D receptor is critical for ligand binding and transcriptional activation

Journal of Bone and Mineral Research

Volumn 16, Issue 1, 2001, Pages 39-45

  Solomon, Cynthia ^a   Macoritto, Michael ^a   Gao, Xiao Ling ^b   White, John H ^a,b   Kremer, Richard ^a  

^a ROYAL VICTORIA HOSPITAL   (Canada)

^b MCGILL UNIVERSITY   (Canada)

Author keywords

1,25 dihydroxyvitamin D3; Coactivators; Ligand binding; Tryptophan; Vitamin D receptor

Indexed keywords

ALANINE; CALCITRIOL; LIGAND; PHENYLALANINE; TRYPTOPHAN; VITAMIN D RECEPTOR;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; GENE TARGETING; GENETIC TRANSCRIPTION; LIGAND BINDING; NONHUMAN; STRUCTURE ACTIVITY RELATION; TRANSACTIVATION;

AMINO ACID SUBSTITUTION; ANIMALS; BLOTTING, WESTERN; COS CELLS; DIMERIZATION; HISTONE ACETYLTRANSFERASES; HUMANS; LIGANDS; MUTATION; PROTEIN BINDING; RECEPTORS, CALCITRIOL; RECEPTORS, RETINOIC ACID; RECOMBINANT FUSION PROTEINS; RETINOID X RECEPTORS; TRANS-ACTIVATION (GENETICS); TRANSCRIPTION FACTORS; TRANSFECTION; TRYPTOPHAN; VITAMIN D;

EID: 0035167829     PISSN: 08840431     EISSN: None     Source Type: Journal    
DOI: 10.1359/jbmr.2001.16.1.39     Document Type: Article

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