Vitamin D receptors from patients with resistance to 1,25- dihydroxyvitamin D3: Point mutations confer reduced transactivation in response to ligand and impaired interaction with the retinoid X receptor heterodimeric partner

Molecular Endocrinology

Volumn 10, Issue 12, 1996, Pages 1617-1631

  Whitfield, G Kerr ^a   Selznick, Sanford H ^a   Haussler, Carol A ^a   Hsieh, Jui Cheng ^a   Galligan, Michael A ^a   Jurutka, Peter W ^a   Thompson, Paul D ^a   Lee, Stanley M ^b   Zerwekh, Joseph E ^c   Haussler, Mark R ^a  

^a University of Arizona   (United States)

^b VANDERBILT UNIVERSITY   (United States)

^c UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCITRIOL; CALCITRIOL RECEPTOR; LIGAND; RETINOID; RETINOID X RECEPTOR;

ARTICLE; DIMERIZATION; DNA BINDING; FIBROBLAST; HUMAN; HUMAN CELL; LIGAND BINDING; POINT MUTATION; PRIORITY JOURNAL; PROTEIN INTERACTION; TRANSACTIVATION; VITAMIN D RESISTANT RICKETS;

ADOLESCENT; ADULT; AMINO ACID SEQUENCE; ANIMALS; CALCITRIOL; CHILD, PRESCHOOL; CLONING, MOLECULAR; COS CELLS; DNA, COMPLEMENTARY; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG RESISTANCE; FEMALE; FIBROBLASTS; GENES, DOMINANT; HUMANS; HYPOCALCEMIA; INFANT; METABOLIC DISEASES; MOLECULAR SEQUENCE DATA; PHENOTYPE; POINT MUTATION; PROTEIN CONFORMATION; RECEPTORS, CALCITRIOL; RECEPTORS, RETINOIC ACID; RECOMBINANT PROTEINS; RETINOID X RECEPTORS; TRANS-ACTIVATION (GENETICS); TRANSCRIPTION FACTORS; TRANSFECTION;

EID: 10544241193     PISSN: 08888809     EISSN: None     Source Type: Journal    
DOI: 10.1210/me.10.12.1617     Document Type: Article

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