GSP-dependent protein secretion in Gram-negative bacteria: The Xcp system of Pseudomonas aeruginosa

FEMS Microbiology Reviews

Volumn 22, Issue 3, 1998, Pages 177-198

  Filloux, Alain ^a   Michel, Gérard ^a   Bally, Marc ^a  

^a CNRS and Aix Marseille University   (France)

Author keywords

General secretory pathway; Gsp; Protein secretion; Pseudomonas aeruginosa; Xcp

Indexed keywords

BACTERIAL PROTEIN; BINDING PROTEIN; PEPTIDASE; SIGNAL PEPTIDE;

BACTERIAL MEMBRANE; BACTERIAL OUTER MEMBRANE; CYTOPLASM; GRAM NEGATIVE BACTERIUM; HYDROPHOBICITY; MEMBRANE MODEL; MEMBRANE STRUCTURE; NONHUMAN; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN SECRETION; PROTEIN TRANSPORT; PSEUDOMONAS AERUGINOSA; REVIEW;

AMINO ACID SEQUENCE; ASPARTIC ENDOPEPTIDASES; BACTERIAL PROTEINS; ENDOPEPTIDASES; FIMBRIAE PROTEINS; GRAM-NEGATIVE BACTERIA; MEMBRANE GLYCOPROTEINS; MEMBRANE PROTEINS; MEMBRANE TRANSPORT PROTEINS; MOLECULAR SEQUENCE DATA; PSEUDOMONAS AERUGINOSA; SEQUENCE ALIGNMENT; SERINE ENDOPEPTIDASES;

NEGIBACTERIA; PSEUDOMONAS; PSEUDOMONAS AERUGINOSA;

EID: 0031754788     PISSN: 01686445     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-6445(98)00013-8     Document Type: Review

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123. Strom, M.S., Nunn, D. and Lory, S. (1991) Multiple roles of the pilus biogenesis protein PiID: involvement of PilD in excretion of enzymes from Pseudomonas aeruginosa. J. Bacteriol. 173, 1175-1180.
124. Missiakas, D. and Raina, S. (1997) Protein folding in the bacterial periplasm. J. Bacteriol. 179, 2465-2471.
125. Shevchik, V.E., Bortoli-German, I., Robert-Baudouy, J., Robinet, S., Barras, F. and Condemine, G. (1995) Differential effect of dsbA and dsbC mutations on extracellular enzyme secretion in Erwinia chrysanthemi. Mol. Microbiol. 16, 745-753.
126. Peek, J.A. and Taylor, R.K. (1992) Characterization of a periplasmic thiol: disulphide interchange protein required for the functional maturation of secreted virulence factors of Vibrio cholerae. Proc. Natl. Acad. Sci. USA 89, 6210-6214.
127. Yu, J., Webb, H. and Hirst, T.R. (1992) A homologue of the Escherichia coli DsbA protein involved in disulphide bond formation is required for enterotoxin biogenesis in Vibrio cholerae. Mol. Microbiol. 6, 1949-1958.
128. Sauvonnet, N. and Pugsley, A.P. (1998) The requirement for DsbA in pullulanase secretion is independent of disulphide bond formation in the enzyme. Mol. Microbiol. 27, 661-667.
129. Bortoli-German, I., Brun, E., Py, B., Chippaux, M. and Barras, F. (1994) Periplasmic disulphide bond formation is essential for cellulase secretion by the plant pathogen Erwinia chrysanthemi. Mol. Microbiol. 11, 545-553.
130. Brumlik, M.J., Gisou van der Goot, F., Wong, K.R. and Buckley, J.T. (1997) The disulfide bond in the Aeromonas hydrophila lipase/acyltransferase stabilizes the structure but is not required for secretion or activity. J. Bacteriol. 179, 3116-3121.
131. Hirst, T.R. and Holmgren, J. (1987) Conformation of protein secreted across bacterial outer membranes: a study of enterotoxin translocation from Vibrio cholerae. Proc. Natl. Acad. Sci. USA 84, 7418-7422.
132. Hardie, K.R., Schulze, A., Parker, M.W. and Buckley, J.T. (1995) Vibrio spp. secrete proaerolysin as a folded dimer without the need for disulphide bond formation. Mol. Microbiol. 17, 1035-1044.
133. Parker, M.W., Buckley, J.T., Postma, J.P.M., Tucker, A.D., Leonard, K., Pattus, F. and Tsernoglou, D. (1994) Structure of the Aeromonas toxin proaerolysin in its water-soluble and membrane-channel states. Nature 367, 292-295.
134. Frenken, L.G.J., Bos, J.W., Visser, C., Müller, W., Tommassen, J. and Verrips, C.T. (1993) An accessory gene, lipB, required for the production of active Pseudomonas glumae lipase. Mol. Microbiol. 9, 579-589.
135. Jaeger, K.E., Ransac, S., Dijkstra, B.W., Colson, C., van Heuvel, M. and Misset, O. (1994) Bacterial lipases. FEMS Microbiol. Rev. 15, 29-63.
136. Kessler, E. and Safrin, M. (1994) The propeptide of Pseudomonas aeruginosa elastase acts as an elastase inhibitor. J. Biol. Chem. 269, 22726-22731.
137. McIver, K.S., Kessler, E., Olson, J.C. and Ohman, D.E. (1995) The elastase propeptide functions as an intramolecular chaperone required for elastase activity and secretion in Pseudomonas aeruginosa. Mol. Microbiol. 18, 877-889.
138. Braun, P., Tommassen, J. and Filloux, A. (1996) Role of the propeptide in folding and secretion of elastase of Pseudomonas aeruginosa. Mol. Microbiol. 19, 297-306.
139. Cota-Gomez, A., Vasil, A.I., Kadurugamuwa, J., Beveridge, T.J., Schweizer, H.P. and Vasil, M.L. (1997) PlcR1 and PlcR2 are putative calcium-binding proteins required for secretion of the hemolytic phospholipase C of Pseudomonas aeruginosa. Infect. Immun. 65, 2904-2913.
140. Py, B., Chippaux, M. and Barras, F. (1993) Mutagenesis of cellulase EGZ for studying the general protein secretory pathway in Erwinia chrysanthemi. Mol. Microbiol. 7, 785-793.
141. Wong, K.R. and Buckley, J.T. (1991) Site-directed mutagenesis of a single tryptophan near the middle of the channel-forming toxin aerolysin inhibits its transfer across the outer membrane of Aeromonas salmonicida. J. Biol. Chem. 266, 14451-14456.
142. Sauvonnet, N., Poquet, I. and Pugsley, A.P. (1995) Extracellular secretion of pullulanase is unaffected by minor sequence changes but is usually prevented by adding reporter proteins to its N- or C-terminal end. J. Bacteriol. 177, 5238-5246.
143. Kornacker, M.G. and Pugsley, A.P. (1990) The normally periplasmic enzyme β-lactamase is specifically and efficiently translocated through the Escherichia coli outer membrane when it is fused to the cell-surface enzyme pullulanase. Mol. Microbiol. 4, 1101-1109.
144. Palomäki, T. and Saarilahti, H.T. (1995) The extreme C-terminus is required for secretion of both the native polygalacturonase (PehA) and PehA-Bla hybrid proteins in Erwinia carotovora subsp. carotovora. Mol. Microbiol. 17, 449-459.
145. Sauvonnet, N. and Pugsley, A.P. (1996) Identification of two regions of Klebsiella oxytoca pullulanase that together are capable of promoting β-lactamase secretion by the general secretory pathway. Mol. Microbiol. 22, 1-7.
146. Lu, H.-M. and Lory, S. (1996) A specific targeting domain in mature exotoxin A is required for its extracellular secretion from Pseudomonas aeruginosa. EMBO J. 15, 429-436.
147. McVay, C.S. and Hamood, A.N. (1995) Toxin A secretion in Pseudomonas aeruginosa: the role of the first 30 amino acids of the mature toxin. Mol. Gen. Genet. 249, 515-525.
148. Yoder, M.D., Keen, N.T. and Jurnak, F. (1993) New domain motif: The structure of pectate lyase C, a secreted plant virulence factor. Science 260, 1503-1507.
149. Lauer, P., Albertson, N.H. and Koomey, M. (1993) Conservation of genes encoding components of a type IV pilus assembly/two-step protein export pathway in Neisseria gonorrhoeae. Mol. Microbiol. 8, 357-368.
150. Ogierman, M.A., Zabihi, S., Mourtzios, L. and Manning, P.A. (1993) Genetic organization and sequence of the promoter-distal region of the tcp gene cluster of Vibrio cholerae. Gene 126, 51-60.
151. Whitchurch, C.B., Hobbs, M., Livingston, S.P., Krishnapillai, V. and Mattick, J.S. (1991) Characterisation of a Pseudomonas aeruginosa twitching motility gene and evidence for a specialised protein export system widespread in eubacteria. Gene 101, 33-44.
152. Dubnau, D. (1997) Binding and transport of transforming DNA by Bacillus subtilis: the role of type-IV pilin-like proteins - a review. Gene 192, 191-198.
153. Mattick, J.S. and Alm, R.A. (1995) Common architecture of type 4 fimbriae and complexes involved in macromolecular traffic. Trends Microbiol. 3, 411-413.
154. Kagami, Y., Ratliff, M., Surber, M., Martinez, A. and Nunn, D.N. (1998) Type II protein secretion by Pseudomonas aeruginosa: genetic suppression of a conditional mutation in the pilin-like component XcpT by the cytoplasmic component XcpR. Mol. Microbiol. 27, 221-233.
155. Whitchurch, C.B. and Mattick, J.S. (1994) Characterization of a gene, pilU, required for twitching motility but not phage sensitivity in Pseudomonas aeruginosa. Mol. Microbiol. 13, 1079-1091.