Protective effects of dietary docosahexaenoic acid against kainate-induced retinal degeneration in rats

Investigative Ophthalmology and Visual Science

Volumn 42, Issue 1, 2001, Pages 216-221

  Mizota, A ^a   Sato, E ^a   Taniai, M ^a   Adachi Usami, E ^a   Nishikawa, M ^a  

^a CHIBA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ARACHIDONIC ACID; DOCOSAHEXAENOIC ACID; KAINIC ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD LEVEL; CONTROLLED STUDY; DIET SUPPLEMENTATION; ELECTRORETINOGRAM; FEMALE; HISTOPATHOLOGY; NERVE EXCITABILITY; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; RAT; RETINA BIPOLAR GANGLION CELL; RETINA DEGENERATION; RETINA GANGLION CELL;

ANIMALS; ARACHIDONIC ACID; DIETARY FATS, UNSATURATED; DOCOSAHEXAENOIC ACIDS; ELECTRORETINOGRAPHY; EXCITATORY AMINO ACID AGONISTS; FEMALE; KAINIC ACID; RATS; RATS, WISTAR; RETINA; RETINAL DEGENERATION;

EID: 0035166264     PISSN: 01460404     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (43)

1. Distribution of four potential transmitter amino acids in monkey retina
2. The distribution of amino acids within the rat retina
3. Amino acid neurotransmitters in the retina: A functional overview
4. The toxic effect of sodium L-glutamate on the inner layers of the retina
5. Kainic acid: The neurotoxic breakthrough
6. Changes of electroretinogram and neurochemical aspects of GABAergic neurons of retina after intraocular injection of kainic acid in rats
7. Molecular diversity of glutamate receptors and implications for brain function
8. Chemistry and metabolism of lipids in the vertebrate retina
9. Membrane fatty acids associated with the electrical response in visual excitation
10. Visual membranes: Specificity of fatty acid precursors for the electrical response to illumination
11. Effect of the dietary alpha-linolenate/linoleate balance on lipid compositions and learning ability of rats, Part II: Discrimination process, extinction process, and glycolipid compositions
12. Dietary omega-3 fatty acid deficiency and visual loss in infant rhesus monkeys
13. Effect of dietary omega-3 fatty acids on retinal function of very-low-birth-weight neonates
14. Retinal development in very low-birth-weight infants fed diets differing in omega-3 fatty acids
15. Apoptosis of retinal photoreceptors during development in vitro: Protective effect of docosahexaenoic acid
16. Docosahexaenoic acid is required for the survival of rat retinal photoreceptors in vitro
17. Biochemical and functional effects of prenatal and postnatal omega 3 fatty acid deficiency on retina and brain in rhesus monkeys
18. Effects of supplementation with omega 3 long-chain polyunsaturated fatty acids on retinal and cortical development in premature infants
19. Polydipsia in rhesus monkeys deficient in omega-3 fatty acids
20. Docosahexaenoic acid in red blood cells of patients with X-linked retinitis pigmentosa
21. Sperm abnormalities in retinitis pigmentosa
22. Excitatory amino acid involvement in retinal degenaration
23. A molecular biological study on retinitis pigmentosa
24. Influence of excitatory amino acids and ischemia on rat retinal choline acetyltransferase-containing cells
25. Local hypothermia protects the retina from ischaemic injury in vitrectomy
26. Functions of the two glutamate transporters GLAST and GLT-1 in the retina
27. Elevated glutamate levels in the vitreous body of humans and monkeys with glaucoma
28. Excitatory amino acid receptors, neural membrane phospholipid metabolism and neurological disorders
29. Dietary N-3 fatty acids inhibit ischaemic and excitotoxic brain damage in the rat
30. Potentiation of NMDA receptors currents by arachidonic acid
31. Facilitatory effect of docosahexaenoic acid on N-methyl-D-aspartate response in pyramidal neurones of rat cerebral cortex
32. A simple method for the isolation and purification of total lipids from animal tissues
33. Dose response effect of dietary docosahexaenoic acid on fatty acid profiles of serum and tissue lipids in rats
34. Alteration of electroretinogram by intravitreal kainic acid in the rat
35. Selective reduction of oscillatory potentials and pattern electroretinograms after retinal ganglion cell damage by disease in humans or by kainic acid toxicity in cats
36. Effect of kainic acid and NMDA on the pattern electroretinogram, the scotopic threshold response, the oscillatory potentials and the electroretinogram in the urethane anaesthetized cat
37. Kainic acid: Neurotoxic effects after intraocular injection
38. Dose-dependent effects of intravitreal kainic acid on specific cell types in chicken retina
39. Neurotoxic effects of kainic acid on developing chick retina
40. Intravitreal kainic acid permanently eliminates off-pathways from chicken retina
41. Neurotoxic action of kainic acid in the isolated toad and goldfish retina. Part II: Mechanism of action
42. Diversity of glutamate receptors in the mammalian retina
43. Localization of receptors for kainic acid on neurons in the inner nuclear layer of retina