Increased concentrations of soluble CD40 ligand, RANTES and GRO-α in preeclampsia - Possible role of platelet activation

Thrombosis and Haemostasis

Volumn 86, Issue 5, 2001, Pages 1272-1276

  Mellembakken, J R ^a   Solum, N O ^a   Ueland, T ^a   Videm, V ^a   Aukrust, P ^a  

^a OSLO UNIVERSITY HOSPITAL   (Norway)

Author keywords

CD40L; GRO ; Platelets; Preeclampsia; RANTES; SFLLRN

Indexed keywords

AUTACOID; CHEMOKINE; GLYCOPROTEIN GP 39; GROWTH RELATED ONCOGENE ALPHA; RANTES; THROMBIN RECEPTOR ACTIVATING PEPTIDE; UNCLASSIFIED DRUG; CD40 LIGAND; CHEMOTACTIC FACTOR; GROWTH REGULATED PROTEIN; PEPTIDE FRAGMENT; SIGNAL PEPTIDE; THROMBIN RECEPTOR PEPTIDE (42 47); THROMBIN RECEPTOR PEPTIDE (42-47);

ADULT; ARTICLE; BLOOD PRESSURE; CELL LEVEL; CELL STIMULATION; CLINICAL ARTICLE; COMPARATIVE STUDY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; ENDOTHELIUM CELL; ENDOTHELIUM LESION; ENZYME IMMUNOASSAY; FEMALE; HUMAN; HUMAN CELL; IN VITRO STUDY; INFLAMMATION; PREECLAMPSIA; PREGNANCY; PRIORITY JOURNAL; PROTEIN SECRETION; THROMBOCYTE; THROMBOCYTE ACTIVATION; THROMBOCYTE COUNT; THROMBOCYTE RICH PLASMA; BLOOD; CASE CONTROL STUDY; DRUG EFFECT; SOLUBILITY;

ADULT; BLOOD PLATELETS; CASE-CONTROL STUDIES; CD40 LIGAND; CHEMOKINES; CHEMOTACTIC FACTORS; FEMALE; HUMAN; INFLAMMATION MEDIATORS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; PEPTIDE FRAGMENTS; PLATELET ACTIVATION; PRE-ECLAMPSIA; PREGNANCY; RANTES; SOLUBILITY; SUPPORT, NON-U.S. GOV'T;

EID: 0035164359     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-0037-1616061     Document Type: Article

References (31)

1. The classification and definition of the hypertensive disorders of pregnancy
2. Preeclampsia: An excessive maternal inflammatory response to pregnancy
3. Preeclampsia: An endothelial cell disorder
4. Pre-eclampsia: More than pregnancy-induced hypertension
5. Flow cytometric detection of activated platelets in pregnant women prior to the development of pre-eclampsia
6. Experimental eclampsia. An electron microscope study and review
7. Coagulation, fibrinolysis and platelet function in pre-eclampsia, essential hypertension and placental insufficiency
8. CD40 ligand on activated platelets triggers an inflammatory reaction of endothelial cells
9. Interleukin-8 and related chemotactic cytokines - CXC and CC chemokines
10. Activated polymorphonuclear leukocytes stimulate platelet function
11. Therapeutic potential for blockade of the CD40 ligand, gp39
12. Enhanced activation of platelets with abnormal release of RANTES in human immunodeficiency virus type 1 infection
13. The role of CD40-CD154 interactions in the regulation of cell mediated immunity
14. Enhanced levels of soluble and membrane-bound CD40 ligand in patients with unstable angina. Possible reflection of T lymphocyte and platelet involvement in the pathogenesis of acute coronary syndromes
15. Activated platelets induce tissue factor expression on human umbilical vein endothelial cells by ligation of CD40
16. Coagulation and fibrinolytic systems in pre-eclampsia and ecclampsia
17. A role for the novel cytokine RANTES in pregnancy and parturition
18. GRO alpha in the fetomaternal and amniotic fluid compartments during pregnancy and parturition
19. Maternal neutrophil apoptosis in normal pregnancy, preeclampsia, and normotensive intrauterine growth restriction
20. CXC chemokine suppression of polymorphonuclear leukocyte apoptosis and preservation of function is oxidative stress independent
21. Abnormal platelet function in pre-eclampsia
22. Analysis of CD9, CD32 and p67 signalling: Use of degranulated platelets indicates direct involvement of CD9 and p67 in integrin activation
23. In vivo tracking of platelets: Circulating degranulated platelets rapidly lose surface P-selectin but continue to circulate and function
24. Impaired platelet function correlates with multi-organ dysfunction
25. CXC-chemokines, a new group of cytokines in congestive heart failure - Possible role of platelets and monocytes
26. Activated platelets signal chemokine synthesis by human monocytes
27. Platelet-leukocyte cross talk in whole blood
28. Leukocyte-leukocyte interactions mediated by platelet microparticles under flow
29. Functional expression of CCR1, CCR3, CCR4, and CXCR4 chemokine receptors on human platelets
30. Neutrophil activation in pregnancy-induced hypertension
31. Complement, neutrophil and macrophage activation in women with severe preeclampsia and the syndrome of hemolysis, elevated liver enzymes and low platelet count