Efficient coupling of ligand binding to channel opening by the binding domain of a modulatory (β) subunit of the olfactory cyclic nucleotide-gated channel

Journal of General Physiology

Volumn 118, Issue 5, 2001, Pages 523-545

  Young, E C ^a   Sciubba, D M ^a   Siegelbaum, S A ^a  

^a Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

Allosteric activation; cAMP; cGMP; Ligand gated channels; Thermodynamic linkage

Indexed keywords

ANIMAL CELL; ARTICLE; CHANNEL GATING; LIGAND BINDING; MOLECULAR INTERACTION; NONHUMAN; SIGNAL TRANSDUCTION; SMELLING; STRUCTURE ACTIVITY RELATION; THERMODYNAMICS; XENOPUS;

ANIMALS; BINDING SITES; CHIMERA; CYCLIC AMP; CYCLIC GMP; ION CHANNELS; ISOMERISM; LIGANDS; OOCYTES; RATS; SIGNAL TRANSDUCTION; THERMODYNAMICS; XENOPUS;

EID: 0035163146     PISSN: 00221295     EISSN: None     Source Type: Journal    
DOI: 10.1085/jgp.118.5.523     Document Type: Article

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