Involvement of endogenous PACAP expression in the activity-dependent survival of mouse cerebellar granule cells

Neuroscience Research

Volumn 39, Issue 1, 2001, Pages 85-93

  Tabuchi, Akiko ^a,b   Koizumi, Motoko ^a   Nakatsubo, Jun ^a   Yaguchi, Takahiro ^a   Tsuda, Masaaki ^a,b  

^a UNIVERSITY OF TOYAMA   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

Apoptosis; Ca2+ channel; Calcium; Cell survival; Cerebellar granule cells; Gene expression; PACAP

Indexed keywords

CALCIUM CHANNEL; HYPOPHYSIS ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE; HYPOPHYSIS ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE RECEPTOR; MESSENGER RNA; POTASSIUM ION;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL CULTURE; CELL MEMBRANE DEPOLARIZATION; CELL SURVIVAL; CEREBELLUM; CONTROLLED STUDY; GENE ACTIVATION; GENE EXPRESSION; GRANULAR CELL; IMMUNOREACTIVITY; IN VITRO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; RECEPTOR BINDING;

ACTINS; ANIMALS; APOPTOSIS; CELL SURVIVAL; CELLS, CULTURED; CEREBELLUM; GENE EXPRESSION; GENES, FOS; MICE; MICE, INBRED ICR; NEUROPEPTIDES; NEUROPROTECTIVE AGENTS; PITUITARY ADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE; RNA, MESSENGER;

EID: 0035163010     PISSN: 01680102     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-0102(00)00200-5     Document Type: Article

References (27)

1. Pituitary adenylate cyclase activating Polypeptide (PACAP) and its receptors: neuroendocrine and endocrine interaction
2. Tissue distribution of PACAP as determined by RIA: high abundance in the rat brain and testis
3. Identification of endogenous sympathetic neuron pituitary adenylate cyclase-activating polypeptide (PACAP): Depolarization regulates production and secretion through induction of multiple propeptide transcripts
4. Interplay of two functionally and structurally distinct domains of the c-fos AU-rich element specifies its mRNA-destabilizing function
5. Type I receptors for PACAP (a neuropeptide even more important than VIP?)
6. Coactivation of secretogranin-II and BDNF genes mediated by calcium signals in mouse cerebellar granule cells
7. The role of depolarization in the survival and differentiation of cerebellar granule cells in culture
8. Requirement for BDNF in activity-dependent survival of cortical neurons
9. Molecular cloning and tissue distribution of a receptor for pituitary adenylate cyclase-activating polypeptide
10. Synergistic induction of pituitary adenylate cyclase activating polypeptide (PACAP) gene expression by nerve growth factor and PACAP in PC12 cells
11. 2+/calmodulin-dependent kinase pathway
12. Attenuation of cell death mediated by membrane depolarization different from that by exogenous BDNF in cultured mouse cerebellar granule cells
13. Brain-derived neurotrophic factor (BDNF) can prevent apoptosis of rat cerebellar granule neurons in culture
14. Developmental regulation of pituitary adenylate cyclase activating polypeptide (PACAP) and its receptor 1 in rat brain: function of PACAP as a neurotrophic factor
15. Binding sites for pituitary adenylate cyclase activating polypeptide (PACAP): comparison with vasoactive intestinal polypeptide (VIP) binding site localization in rat brain sections
16. Isolation of a novel 38 residue-hypothalamic polypeptide which stimulates adenylate cyclase in pituitary cells
17. Activity-dependent expression of parathyroid hormone-related protein (PTHrP) in rat cerebellar granule neurons. Requirement of PTHrP for the activity-dependent survival of granule neurons
18. Structural requirements for the occupancy of pituitary adenylate-cyclase-activating-peptide (PACAP) receptors and adenylate cyclase activation in human neuroblastoma NB-OK-1 cell membranes. Discovery of PACAP(6-38) as a potent antagonist
19. 2+ signals without involvement of de novo AP-1 synthesis
20. Localization and gene expression of the receptor for pituitary adenylate cyclase-activating polypeptide in the rat brain
21. Inducibility of BDNF gene promoter I detected by calcium-phosphate-mediated DNA transfection is confined to neuronal but not to glial cells
22. 2+ channels
23. Neurotrophic and neuroprotective effects of pituitary adenylate cyclase-activating polypeptide (PACAP) on mesencephalic dopaminergic neurons
24. 2+ influx regulates BDNF transcription by a CREB-family transcription factor-dependent mechanism
25. Pituitary adenylate cyclase-activating polypeptides stimulates both c-fos gene expression and cell survival in rat cerebellar granule neurons through activation of the protein kinase A pathway
26. Pituitary adenylate cyclase-activating polypeptide (PACAP-38) protects cerebellar granule neurons from apoptosis by activating the mitogen-activated protein kinase (MAP kinase) pathway
27. Cloning and characterization of the mouse pituitary adenylate cyclase-activating polypeptide (PACAP) gene