The effect of G-CSF on lymphocyte subsets and CD34+ cells in allogeneic stem cell transplantation

Transfusion and Apheresis Science

Volumn 24, Issue 1, 2001, Pages 23-28

  Gürman, Günhan ^a   Dilek, Imdat ^a   Arslan, Önder ^a   Arat, Mutlu ^a   Beksaç, Meral ^a   Ilhan, Osman ^a   Özcan, Muhit ^a   Akan, Hamdi ^a   Dalva, Klara ^a   Konuk, Nahide ^a   Uysal, Akýn ^a   Koç, Haluk ^a  

^a ANKARA UNIVERSITY   (Turkey)

Author keywords

Allogeneic peripheral hematopoietic stem cell transplantation; CD34+ cells; G CSF; Lymphocyte subsets; Peripheral blood mononuclear cell mobilization

Indexed keywords

CD34 ANTIGEN; GRANULOCYTE COLONY STIMULATING FACTOR;

ADULT; APHERESIS; ARTICLE; BIOLOGICAL THERAPY; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFECT; FEMALE; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMAN; HUMAN CELL; HUMAN EXPERIMENT; LYMPHOCYTE SUBPOPULATION; MALE; MONONUCLEAR CELL; NORMAL HUMAN; PERIPHERAL LYMPHOCYTE;

ADOLESCENT; ADULT; ANTIGENS, CD34; FEMALE; GRANULOCYTE COLONY-STIMULATING FACTOR; HEMATOPOIETIC STEM CELL MOBILIZATION; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMANS; IMMUNOPHENOTYPING; LEUKAPHERESIS; LYMPHOCYTE SUBSETS; MALE; MIDDLE AGED; TRANSPLANTATION, ISOGENEIC;

EID: 0035161821     PISSN: 14730502     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0955-3886(00)00123-5     Document Type: Article

References (21)

1. Transplantation of allogeneic peripheral blood stem cells mobilized by recombinant human granulocyte colony-stimulating factor
2. Allogeneic blood stem cell transplantation: peripheralization and yield of donor-derived primitive hematopoietic progenitor cells (CD34+ Thy-1dim) and lymphoid subsets, and possible predictors of engraftment and graft-versus-host disease
3. Comparison between once a day vs twice a day G-CSF for mobilization of peripheral blood progenitor cells (PBPC) in normal donors for allogeneic PBPC transplantation
4. Duration of filgrastim mobilization and apheresis yield of CD34+ progenitor cells and lymphoid subsets in normal donors for allogeneic transplantation
5. Hematopoietic and immune recovery after transplantation of cord blood progenitor cells in children
6. Peripheral blood stem cells as an alternative to marrow for allogeneic transplantation
7. Reconstitution of human hematopoietic function with autologous cryopreserved circulating stem cells
8. Allogeneic peripheral blood stem cell transplantation for haematological malignancies - an analysis of kinetics of engraftment and GVHD risk
9. Rapid immunologic reconstitution following transplantation with mobilized peripheral blood stem cells as compared to bone marrow
10. Granulocyte colony-stimulating factor reduces the capacity of blood mononuclear cells to induce graft-versus-host disease: impact on blood progenitor cell transplantation
11. Faster neutrophil and platelet engraftment, but no differences in acute GVHD or survival, using peripheral blood stem cells from related and unrelated donors, compared to bone marrow
12. Optimal timing for collection of PBPC after glycosylated G-CSF administration
13. G-CSF serum pharmacokinetics during peripheral blood progenitor cell mobilization: neutrophil count-adjusted dosage might potentially improve mobilization and be more cost-effective
14. Immunologic phenotype and function in human bone marrow, blood stem cells and umbilical cord blood
15. G-CSF-mobilized peripheral blood progenitor cells for allogeneic transplantation: safety, kinetics of mobilization, and composition of the graft
16. Pretreatment of donor mice with granulocyte colony-stimulating factor polarizes donor T lymphocytes toward type-2 cytokine production and reduces severity of experimental graft-versus-host disease
17. Comparison of haematological recovery times and supportive care requirements of autologous recovery phase peripheral blood stem cell transplants, autologous bone marrow transplants and allogeneic bone marrow transplants
18. Transplantation of allogeneic CD34+ peripheral blood stem cells in patients with advanced hematologic malignancy
19. Primary transplantation of allogeneic peripheral blood progenitor cells mobilized by filgrastim (granulocyte colony-stimulating factor)
20. Lymphocyte content in peripheral blood mononuclear cells collected after the administration of recombinant human granulocyte colony-stimulating factor