Optimal timing for collection of PBPC after glycosylated G-CSF administration

Bone Marrow Transplantation

Volumn 21, Issue 4, 1998, Pages 365-368

  Watts, M J ^a   Addison, I ^a   Ings, S J ^a   Long, S G ^b   Hartley, S ^b   Warrington, S ^c   Boyce, M ^c   Linch, D C ^a,d  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b Chugai Pharma ^*

^c CENTRAL MIDDLESEX HOSPITAL   (United Kingdom)

^d UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Apheresis timing; G CSF; Kinetics; Mobilization; Progenitor cells

Indexed keywords

CD34 ANTIGEN; RECOMBINANT GRANULOCYTE COLONY STIMULATING FACTOR;

ADULT; ARTICLE; BURST FORMING UNIT E; COLONY FORMING CELL; HUMAN; HUMAN CELL; HUMAN EXPERIMENT; MALE; NEUTROPHIL; PERIPHERAL BLOOD STEM CELL; PRIORITY JOURNAL; SUBCUTANEOUS DRUG ADMINISTRATION;

EID: 0031889741     PISSN: 02683369     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bmt.1701099     Document Type: Article

References (17)

1. Gratwohl A, Hermans J, Baldomero H. Blood and marrow transplantation activity in Europe 1995. Bone Marrow Transplant 1997; 19: 407-419.
2. + cells with a different antigenic profile compared with use during steady state hematopoiesis. Bone Marrow Transplant 1994; 14: 827-832.
3. Van Hoef MEHM. Guidelines for efficient peripheral blood progenitor cell collection (review). Neth J Med 1996; 48: 29-37.
4. + progenitors to peripheral blood: impaired mobilization in chronic granulomatous disease and adenosine deaminase-deficient severe combined immunodeficiency disease patients. Blood 1996; 88: 1104-1112.
5. + cells in healthy people. Transf Med 1997; 7: 19-24.
6. Watts MJ, Addison I, Long SG et al. Crossover study of the haematological effects and pharmacokinetics of glycosylated and non-glycosylated G-CSF in healthy volunteers. Br J Haematol 1997; 98: 474-479.
7. Watts MJ, Jones HM, Sullivan AM et al. Accessory cells do not contribute to G-CSF or IL-6 production nor to rapid haematological recovery following peripheral blood stem cell transplantation. Br J Haematol 1995; 91: 767-772.
8. Sato N, Sawada K, Takahashi TA et al. A time course study for optimal harvest of peripheral blood progenitor cells by granulocyte colony-stimulating factor in healthy volunteers. Exp Haematol 1994; 22: 937-978.
9. Yong KL, Linch DC. Differential effects of granulocyte-and granulocyte-macrophage colony-stimulating factors (G-and GM-CSF) on neutrophil adhesion in vitro and in vivo. Eur J Haematol 1992; 5: 251-259.
10. + cell counts and on the collection of peripheral blood stem cells. Transfusion 1996; 36: 601-610.
11. Elliott C, Samson DM, Armitage S et al. When to harvest peripheral blood stem cells after mobilization therapy: prediction of CD34-positive cell yield by preceding day CD34-positive concentration in peripheral blood. J Clin Oncol 1996; 14: 970-973.
12. Hoglund M, Smedmyr B, Simonsson B et al. Dose-dependent mobilisation of haematopoietic progenitor cells in healthy volunteers receiving glycosylated rHu G-CSF. Bone Marrow Transplant 1996; 18: 19-27.
13. Jones HM, Picozzi VJ, Price HT et al. Peripheral blood progenitor harvest following mobilization using G-CSF: experience in collections from 99 normal subjects. Blood 1996; 88: 679a (Abstr. 2705).
14. Waller CF, Bertz H, Wenger MK et al. Mobilization of peripheral blood progenitor cells for allogeneic transplantation: efficacy and toxicity of a high-dose rhG-CSF regimen. Bone Marrow Transplant 1996; 18: 279-283.
15. Höglund M, Bengtsson M, Cour-Chabernaud V et al. Glycosylated rHuG-CSF is more potent than non-glycosylated rHuG-CSF in mobilisation of peripheral blood progenitor cells (PBPC) in healthy volunteers. Blood 1995; 86: 464a.
16. Devereux S, Linch DC, Costa DC et al. Transient leucopenia induced by granulocyte-macrophage colony-stimulating factor (letter). Lancet 1987; ii: 1523-1524.
17. + haematopoietic progenitors. Blood 1996; 88: 1168-1176.