Synthetic peptide and protein domain arrays prepared by the SPOT technology

Comparative and Functional Genomics

Volumn 2, Issue 5, 2001, Pages 307-309

  Schneider Mergener, Jens ^a,b  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b Jerini AG   (Germany)

Author keywords

Antibody; Kinase; Peptide protein chips; Protease; Receptor; SPOT synthesis

Indexed keywords

EPITOPE; PHOSPHOTRANSFERASE; PROTEINASE; PROTEOME; SYNTHETIC PEPTIDE;

AMINO ACID SEQUENCE; ENZYME SPECIFICITY; EPITOPE MAPPING; PEPTIDE MAPPING; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PROTEIN SYNTHESIS; PROTEIN TARGETING; REVIEW; TECHNOLOGY;

EID: 0035160951     PISSN: 15316912     EISSN: None     Source Type: Journal    
DOI: 10.1002/cfg.99     Document Type: Review

References (12)

1. The novel human TNF-receptor p55-associated WD-repeat protein FAN mediates neutral SMase activation
2. Synthesis of native proteins by chemical ligation
3. Peptide and small molecule microarray for high throughput cell adhesion and functional assays
4. Spot synthesis: An easy technique for the positionally addressable, parallel chemical synthesis on a membrane support
5. SPOT-synthesis: Scope and applications. Introduction to: Peptide arrays on membrane supports-synthesis and applications
6. Printing proteins as microarrays for high-throughput function determination
7. Applications of peptide arrays prepared by the SPOT technology
8. Knowledge- and library-based mapping of discontinuous protein-protein-interactions by spot synthesis
9. Synthesis of an array comprising 837 variants of the hYAP WW protein domain
10. Incorporating new ligand specificities into a 38mer WW protein domain applying an array of 6859 WW domain variants prepared by a combination of SPOT synthesis and native chemical ligation
11. For an extensive overview of references on applications of the SPOT technology and recent developments in peptide microarrays
12. Coherent membrane supports for parallel micro-synthesis of bioactive peptides