Exaggerated natriuresis after selective AT1 receptor blockade in Dahl salt-sensitive rats

Clinical and Experimental Hypertension

Volumn 23, Issue 8, 2001, Pages 623-631

  Tallam, L S ^a   Jandhyala, B S ^a  

^a UNIVERSITY OF HOUSTON   (United States)

Author keywords

Angiotensin II (Ang II); Candesartan; Renal function; Salt sensitivity

Indexed keywords

ANGIOTENSIN; ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN 1 RECEPTOR ANTAGONIST; ANGIOTENSIN RECEPTOR; CANDESARTAN; RENIN; SODIUM; SODIUM CHLORIDE; THIOBUTABARBITAL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; GENE OVEREXPRESSION; HEMODYNAMICS; HORMONE ACTION; HYPERTENSION; KIDNEY CORTEX; KIDNEY FUNCTION; KIDNEY TUBULE EPITHELIUM; MALE; NATRIURESIS; NONHUMAN; PATHOGENESIS; RAT; RAT STRAIN; RECEPTOR DENSITY; SODIUM RETENTION; STRAIN DIFFERENCE;

ANIMALS; ANTIHYPERTENSIVE AGENTS; BENZIMIDAZOLES; HEMODYNAMIC PROCESSES; HUMANS; HYPERTENSION; KIDNEY; MALE; NATRIURESIS; RADIOLIGAND ASSAY; RATS; RATS, INBRED DAHL; RECEPTOR, ANGIOTENSIN, TYPE 1; RECEPTORS, ANGIOTENSIN; RENIN; SODIUM, DIETARY; TETRAZOLES;

EID: 0035159399     PISSN: 10641963     EISSN: None     Source Type: Journal    
DOI: 10.1081/CEH-100107392     Document Type: Article

References (24)

1. Salt-more adverse effects
2. Primary role of renal homographs in setting chronic blood pressure levels in rats
3. Role of genetic factors in susceptibility to experimental hypertension due to chronic salt ingestion
4. Hypertension in Dahl salt-sensitive rats: Biochemical and immunohistochemical studies
5. AT-1 receptor regulation in salt-sensitive hypertension
6. Abnormal regulation of proximal tubule renin mRNA in the Dahl/Rapp salt-sensitive rats
7. Salt-sensitive hypertension: Lessons from animal models
8. Impaired renal vasodilation and urinary cGMP excretion in Dahl salt-sensitive rats
9. Role of natriuretic peptide type C receptor in Dahl salt-sensitive hypertensive rats
10. Possible mechanisms for salt-induced hypertension in Dahl salt-sensitive rats
11. Pathophysiological roles of endothelin-1 in Dahl salt-sensitive hypertension
12. Significance of AT-1 receptor blockade and ACE inhibition in obese Zucker rats
13. Renal dopamine DA1 receptor coupling with G(S) and G(q/11) in spontaneously hypertensive rats
14. Sodium gradient and sodium plus potassium gradient dependent L-glutamate uptake in renal basolateral membrane vesicles
15. Angiotensin-II binding sites on isolated rat renal brush border membranes
16. In vitro autoradiography reveals predominantly AT-1 angiotensin-II receptors in rat kidney
17. Implications of local angiotensin-II production in cardiovascular physiology and pharmacology
18. Renal responses to AT1 receptor blockade
19. The paradox of lowrenin state in diabetic nephropathy
20. Mechanism of natriuresis during intrarenal infusion of prostaglandins
21. Renal hemodynamics and excretory responses to bradykinin in anaesthetized dogs
22. Role of angiotensin type 2 receptor in the regulation of blood pressure and renal function
23. Renal, intestinal, and adrenal responses to sodium loading in Dahl-Iwaii salt-sensitive and salt-resistant rats