Supplementation of islet culture medium with insulin may have a beneficial effect on islet secretory function

Pancreas

Volumn 22, Issue 1, 2001, Pages 72-74

  Clayton, Heather ^a,b   Turner, Julie ^a   Swift, Sue ^a   James, Roger ^a   Bell, Peter ^a  

^a UNIVERSITY OF LEICESTER   (United Kingdom)

^b LEICESTER GENERAL HOSPITAL   (United Kingdom)

Author keywords

Anoikis; Apoptosis; Insulin; Insulin secretion; Islet culture; Perifusion

Indexed keywords

INSULIN;

ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL GROWTH; CELL ISOLATION; CELL SECRETION; CELL SURVIVAL; CONCENTRATION RESPONSE; CONTROLLED STUDY; CULTURE MEDIUM; HUMAN; HUMAN TISSUE; NONHUMAN; PANCREAS ISLET; PRIORITY JOURNAL; SPECIES DIFFERENCE; SWINE; TISSUE CULTURE;

ANIMALS; ANOIKIS; CELLS, CULTURED; CULTURE MEDIA; HUMANS; INSULIN; ISLETS OF LANGERHANS; SWINE;

EID: 0035158231     PISSN: 08853177     EISSN: None     Source Type: Journal    
DOI: 10.1097/00006676-200101000-00013     Document Type: Article

References (18)

1. Tissue culture isolation and preservation of human cadaveric islets
2. Major histocompatibility complex antigens and murine islet allograft survival
3. A comparison of media supplement methods for the extended culture of human islet tissue
4. Adenoviral transfection of isolated pancreatic islets: A study of programmed cell death (apoptosis) and islet function
5. Disruption of epithelial cell-matrix interactions induces apoptosis
6. Apoptosis occurs in freshly isolated human islets under standard culture conditions
7. Structural and functional changes resulting from islet isolation lead to islet cell death
8. Anoikis, extracellular matrix, and apoptosis factors in isolated cell transplantation
9. Activation and expression of ERK, JNK, and p38 MAP-kinases in isolated islets of Langerhans: Implications for cultured islet survival
10. Activation of the insulin-like growth factor-1 receptor promotes the survival of human keratinocytes following ultraviolet B irradiation
11. Neural apoptosis in the retina during experimental and human diabetes. Early onset and effect of insulin
12. Insulin prevents apoptosis of external granular layer neurons in rat cerebellar slice cultures
13. Automated method for isolation of human pancreatic islets
14. The optimisation of large-scale density gradient isolation of human islets
15. A study of the effect of capsule composition on the viability of cultured alginate/poly1-lysine-encapsulated rat islets
16. Variables in organ donors that affect the recovery of human islets of Langerhans
17. Enhancement of pancreatic islet cell monolayer growth by endothelial cell matrix and insulin