Stimulation of GATA-2 as a mechanism of hydrogen peroxide suppression in hypoxia-induced erythropoietin gene expression

Journal of Cellular Physiology

Volumn 186, Issue 2, 2001, Pages 260-267

  Tabata, Masahiko ^a   Tarumoto, Takahisa ^a   Ohmine, Ken ^a   Furukawa, Yusuke ^a   Hatake, Kiyohiko ^a   Ozawa, Keiya ^a   Hasegawa, Yuichi ^b   Mukai, Harumi ^b   Yamamoto, Masayuki ^b   Imagawa, Shigehiko ^b  

^a JICHI MEDICAL UNIVERSITY   (Japan)

^b UNIVERSITY OF TSUKUBA   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; ERYTHROPOIETIN; HYDROGEN PEROXIDE; MESSENGER RNA; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR GATA 2;

ARTICLE; BINDING SITE; DNA BINDING; ENHANCER REGION; GENE EXPRESSION REGULATION; HEMATOPOIESIS; HEPATOMA CELL; HUMAN; HUMAN CELL; HYPOXIA; OXYGEN TENSION; PRIORITY JOURNAL; PROMOTER REGION;

BINDING SITES; CATALASE; CELL HYPOXIA; DNA-BINDING PROTEINS; ENHANCER ELEMENTS (GENETICS); ERYTHROPOIETIN; GATA2 TRANSCRIPTION FACTOR; GENE EXPRESSION REGULATION; HUMANS; HYDROGEN PEROXIDE; NF-KAPPA B; PROMOTER REGIONS (GENETICS); RECOMBINANT PROTEINS; TRANSCRIPTION FACTORS; TRANSFECTION; TUMOR CELLS, CULTURED; ZINC FINGERS;

EID: 0035157487     PISSN: 00219541     EISSN: None     Source Type: Journal    
DOI: 10.1002/1097-4652(200002)186:2<260::AID-JCP1025>3.0.CO;2-K     Document Type: Article

References (34)

1. An essential role for p300/CBP in the cellular response to hypoxia
2. Hypoxic induction of the human erythropoietin gene: Cooperation between the promoter and enhancer, each of which contains steroid receptor response elements
3. Oxygen sensing and molecular adaptation to hypoxia
4. Hypoxia and mitochondrial inhibiters regulate expression of glucose transporter-1 via distinct cis-acting sequences
5. Control of globin gene transcription
6. Role of hydrogen peroxide in hypoxia-induced erythropoietin production
7. Role of hydrogen peroxide in hypoxia-induced expression of the erythropoietin and the vascular endothelial growth factor genes
8. Oxygen-regulated control elements in the phosphoglycerate kinase 1 and lactate dehydrogenase A genes: Similarities with the erythropoietin 3′ enhancer
9. The orphan receptor hepatic nuclear factor 4 functions as a transcriptional activator for tissue-specific and hypoxia-specific erythropoietin gene expression and is antagonized by EAR3/COUP-TF-1
10. The regulated expression of erythropoietin by two human hepatoma cell lines
11. Regulation of the erythropoietin gene: Evidence that the oxygen sensor is a heme protein
12. Studies on erythropoiesis. V. The effect of cobalt on the production of erythropoietin
13. 2)
14. Activation of hypoxia-inducible transcription factor depends primarily upon redox-sensitive stabilization of it's α subunit
15. Erythropoietin gene regulation depends on heme-dependent oxygen sensing and assembly of interacting transcription factors
16. 2-dependent degradation domain via the ubiquitin-proteasome pathway
17. Regulatory elements of the erythropoietin gene
18. Erythropoietin gene expression by hydrogen peroxide
19. Negative regulation of the erythropoietin gene expression by the GATA transcription factors
20. Nature
21. Transcriptional regulation of the rat vascular endothelial growth factor gene by hypoxia
22. Transcription factor GATA-2 is expressed in erythroid, early myeloid, and CD34+ human leukemia-derived cell lines
23. A novel rapid assay for chloramphenicol acetyltransferase gene expression
24. Luciferase reporter gene vectors for analysis of promoters and enhancers
25. Globin gene regulation and switching
26. Expression of δ-aminolevulinate synthase in avian cells: Separate genes encode erythroid specific and non-specific isozymes
27. Hypoxia-inducible nuclear factors bind to an enhancer element located 3′ to the human erythropoeitin gene
28. Cell-type specific and hypoxia-inducible expression of the human erythropoietin gene in transgenic mice
29. A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation
30. Regulation of GATA-2 phosphorylation by mitogen-activated protein kinase and interleukin-3
31. A nonerythroid GATA-binding protein is required for function of the human preproendothelin-1 promoter in endothelial cells
32. Activity and tissue-specific expression of the transcription factor NF-E1 multi gene family
33. Liver as the primary site of erythropoietin formation in the fetus