Crystal structure of 3,4-dihydroxy-2-butanone 4-phosphate synthase of riboflavin biosynthesis

Structure

Volumn 9, Issue 1, 2001, Pages 11-18

  Liao, D I ^a   Calabrese, J C ^a   Wawrzak, Z ^a   Viitanen, P V ^a   Jordan, D B ^a  

^a DUPONT COMPANY   (United States)

Author keywords

Antimicrobial target; Dihydroxybutanone phosphate synthase; Riboflavin bio synthesis; Skeletal rearrangement; Structure based design

Indexed keywords

3,4 DIHYDROXY 2 BUTANONE 4 PHOSPHATE SYNTHASE; ASPARTIC ACID DERIVATIVE; CYSTEINE DERIVATIVE; GLUTAMIC ACID DERIVATIVE; HISTIDINE DERIVATIVE; RIBOFLAVIN; SYNTHETASE; UNCLASSIFIED DRUG;

ARTICLE; BIOSYNTHESIS; CATALYSIS; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME STRUCTURE; ENZYME SUBUNIT; HYDROGEN BOND; HYDROPHOBICITY; PRIORITY JOURNAL; PROTEIN FOLDING;

ASPARTIC ACID; BINDING SITES; CATALYSIS; CRYSTALLOGRAPHY, X-RAY; CYSTEINE; DIMERIZATION; ESCHERICHIA COLI; GLUTAMIC ACID; HISTIDINE; INTRAMOLECULAR TRANSFERASES; MAGNESIUM; MODELS, CHEMICAL; MODELS, MOLECULAR; PROTEIN STRUCTURE, SECONDARY; RIBOFLAVIN; RIBOFLAVIN SYNTHASE;

EID: 0035155856     PISSN: 09692126     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0969-2126(00)00550-5     Document Type: Article

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