Sputum endothelin-1 is increased in cystic fibrosis and chronic obstructive pulmonary disease

European Respiratory Journal

Volumn 13, Issue 6, 1999, Pages 1288-1292

  Chalmers, G W ^a,b   Macleod, K J ^a   Sriram, S ^a   Thomson, L J ^a   McSharry, C ^a   Stack, B H R ^a   Thomson, N C ^a  

^a WESTERN INFIRMARY   (United Kingdom)

^b NHS GREATER GLASGOW AND CLYDE   (United Kingdom)

Author keywords

Chronic obstructive; Cystic fibrosis; Endothelin 1; Pulmonary disease; Sputum

Indexed keywords

ENDOTHELIN 1;

ADOLESCENT; ADULT; AGED; AIRWAY OBSTRUCTION; ARTICLE; BLOOD LEVEL; BRONCHOSPASM; CHRONIC OBSTRUCTIVE LUNG DISEASE; CLINICAL ARTICLE; CONTROLLED STUDY; CYSTIC FIBROSIS; FEMALE; HUMAN; HUMAN CELL; MALE; MITOGENESIS; NEUTROPHILIA; PRIORITY JOURNAL; SALIVA LEVEL; SPUTUM CYTODIAGNOSIS; SPUTUM LEVEL;

ADOLESCENT; ADULT; AGED; CELL COUNT; CYSTIC FIBROSIS; ENDOTHELIN-1; FEMALE; HUMANS; LUNG DISEASES, OBSTRUCTIVE; MALE; MIDDLE AGED; SPUTUM;

EID: 0032811349     PISSN: 09031936     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1399-3003.1999.13f12.x     Document Type: Article

References (21)

1. Cropp G. The effectiveness of bronchodilators in cystic fibrosis. Am J Med 1996; 100: 19S-29S.
2. Leigh M, Kylander J, Yankaskas J, Boucher R. Cell proliferation in bronchial epithelium and submucosal glands of cystic fibrosis patients. Am J Respir Cell Mol Biol 1995; 12: 605-612.
3. Mattoli S, Mezzetti M, Riva G, Allegra L, Fasoli A. Specific binding of endothelin on human bronchial smooth muscle cells in culture and secretion of endothelin-like material from bronchial epithelial cells. Am J Respir Cell Mol Biol 1990; 3: 145-151.
4. Chalmers G, Little S, Patel K, Thomson N. Endothelin-1-induced bronchoconstriction in asthma. Am J Respir Crit Care Med 1997; 156: 382-388.
5. Noveral J, Rosenberg S, Anbar R, Pawlowski N, Grunstein M. Role of endothelin-1 in regulating proliferation of cultured rabbit airway smooth muscle cells. Am J Physiol 1992; 263: L317-L324.
6. Murlas C, Gulati A, Singh G, Najmabadi F. Endothelin-1 stimulates proliferation of normal airway epithelial cells. Biochem Biophys Res Commun 1995; 212: 953-959.
7. Chanez P, Vignola A, Albat B, et al. Involvement of endothelin in mononuclear phagocyte inflammation in asthma. J Allergy Clin Immunol 1996; 98: 412-420.
8. Marini M, Carpi S, Bellini A, Patalano F, Mattoli S. Endothelin-1 increases fibronectin expression in human bronchial epithelial cells. Biochem Biophys Res Commun 1996; 220: 896-899.
9. Marciniak S, Plumpton C, Barker P, Huskisson N, Davenport A. Localisation of immunoreactive endothelin and proendothelin in the human lung. Pulm Pharmacol 1992; 5: 175-182.
10. McKay K, Black J, Diment M, Armour C. Functional and autoradiographic studies of endothelin-1 and endothelin-2 in human bronchi, pulmonary arteries, and airway parasympathetic ganglia. J Cardiovasc Pharmacol 1991; 17: 206-209.
11. Ehrenreich H, Anderson R, Fox C, et al. Endothelins, peptides with potent vasoactive properties are produced by human macrophages. J Exp Med 1990; 172: 1741-1748.
12. Sessa W, Kaw S, Heeker M, Vane J. The biosynthesis of endothelin-1 by human polymorphonuclear leukocytes. Biochem Biophys Res Commun 1991; 174: 613-618.
13. Springall D, Howarth P, Counihan H, Djukanovic R, Holgate S, Polak J. Endothelin immunoreactivity of airway epithelium in asthmatic patients. Lancet 1991; 337: 697-701.
14. Redington A, Springall D, Ghatei M, et al. Endothelin in bronchoalveolar lavage fluid and its relation to airflow obstruction in asthma. Am J Respir Crit Care Med 1995; 151: 1034-1039.
15. Pizzichini M, Popov T, Efthimiadis A, et al. Spontaneous and induced sputum to measure indices of airway inflammation in asthma. Am J Respir Crit Care Med 1996; 154: 866-869.
16. Lam H, Takahashi K, Ghatei M, Suda K, Kanse S, Bloom S. Presence of immunoreactive endothelin in human saliva and rat parotid gland. Peptides 1991; 12: 883-885.
17. Nally J, McCall R, Young L, Wakelam M, Thomson N, McGrath J. Mechanical and biochemical responses to endothelin-1 and endothelin-3 in human bronchi. Eur J Pharmacol 1994; 288: 53-60.
18. Sanchez I, Powell R, Chernick V. Response to inhaled bronchodilators and nonspecific airway hyperreactivity in children with cystic fibrosis. Paediatr Pulmonol 1992; 14: 52-57.
19. Bonfield T, Panuska J, Konstan M, et al. Inflammatory cytokines in cystic fibrosis lungs. Am J Respir Crit Care Med 1995; 152: 2111-2118.
20. Shah A, Church M, Holgate S. Tumour necrosis factor alpha: a potential mediator of asthma. Clin Exp Allergy 1995; 25: 1038-1044.
21. Noguchi S, Kashihara Y. Alterations of airway smooth muscle structure in endothelin-1-infused guinea-pigs in vivo. Am J Respir Crit Care Med 1996; 153: A843.