A precaution in the detection of heterozygotes by sequencing: Comparison of automated DNA sequencing and PCR-restriction fragment length polymorphism methods

Clinical Chemistry

Volumn 47, Issue 1, 2001, Pages 134-137

  Simsek, M ^a   Tanira, M O M ^a   Al Baloushi, K A ^a   Al Barwani, H S ^a   Lawatia, K M ^a   Bayoumi, R A L ^a  

^a SULTAN QABOOS UNIVERSITY   (Oman)

Author keywords

[No Author keywords available]

Indexed keywords

ACYLTRANSFERASE; DNA FRAGMENT; GENE PRODUCT; PROTEIN NAT2; UNCLASSIFIED DRUG;

ALLELISM; ANALYTIC METHOD; ARTICLE; AUTOMATION; CLINICAL ARTICLE; COMPARATIVE GENOMIC HYBRIDIZATION; CONTROLLED STUDY; DNA POLYMORPHISM; DNA SEQUENCE; GENE MUTATION; GENOTYPE; HETEROZYGOSITY; HUMAN; INTERMETHOD COMPARISON; POLYMERASE CHAIN REACTION; RESTRICTION FRAGMENT;

EID: 0035152178     PISSN: 00099147     EISSN: None     Source Type: Journal    
DOI: 10.1093/clinchem/47.1.134     Document Type: Article

References (9)

1. Detection of sickle cell S-globin allele by hybridization with oligonucleotides
2. Allele-specific enzymatic amplification of β-globin genomic DNA for diagnosis of sickle cell anemia
3. Homozygous rapid arylamine N-acetylase (NAT2) genotype as a susceptibility factor for lung cancer
4. Screening for point mutations by semi-automated DNA sequencing using sequenase and magnetic beads
5. Peak height patterns in dichloro-rhodamine and energy transfer dye terminator sequencing
6. Pitfalls in N-acetyltransferase 2 genotyping
7. Accuracy of genotyping of a single-nucleotide polymorphism by PCR-ELISA allele-specific oligonucleotide hybridization typing and by amplification refractory mutation system
8. N-Acetyltransferase polymorphism: Comparison of phenotype and genotype in humans
9. Cloning and expression of cDNAs for polymorphic and monomorphic arylamine N-acetyltransferases from human liver