p73 expression in neuroblastoma: A role in the biology of advanced tumors?

Pediatric Hematology and Oncology

Volumn 18, Issue 1, 2001, Pages 37-46

  Matos, Paulo ^a   Isidro, Glória ^a   Vieira, Estér ^b   Lacerda, Ana Forjaz ^b   Martins, António Gentil ^b   Boavida, Maria Guida ^a  

^a NATIONAL INSTITUTE OF HEALTH DR RICARDO JORGE   (Portugal)

^b Intituto Português de Oncologia de Francisco Gentil ^*  (Portugal)

Author keywords

Neuroblastoma; p73; Polymorphisms

Indexed keywords

CYTOSINE; GUANOSINE; PROTEIN P53; PROTEIN P73;

ALLELE; ARTICLE; CANCER STAGING; CARCINOGENESIS; CHROMOSOME 1P; CONTROLLED STUDY; GENE EXPRESSION; HUMAN; HUMAN TISSUE; NEUROBLASTOMA; PROTEIN EXPRESSION; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ADOLESCENT; ALLELES; CHILD; CHILD, PRESCHOOL; DNA-BINDING PROTEINS; GENES, TUMOR SUPPRESSOR; HUMANS; INFANT; INFANT, NEWBORN; NEUROBLASTOMA; NUCLEAR PROTEINS; POLYMERASE CHAIN REACTION; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; TUMOR SUPPRESSOR PROTEINS;

EID: 0035151412     PISSN: 08880018     EISSN: None     Source Type: Journal    
DOI: 10.1080/088800101750059846     Document Type: Article

References (21)

1. Restriction fragment length polymorphism analysis reveals different allele frequency and linkage disequelibrium at locus D1S94 in neuroblastoma patients
2. Fluorescence in situ hybridisation analysis of chromosome 1p36 deletion in human MYCN amplified neuroblastoma
3. Evidence for two tumour suppressor loci on chromosomal bands 1p35-36 involved in neuroblastoma; one probably imprinted, another associated with N-myc amplification
4. Dissociation of suppression of tumourigenicity and differentiation in vitro effected by transfer of single human chromosomes into human neuroblastoma cells
5. Monoallelically expressed gene related to p53 at 1p36, a region frequently deleted in neuroblastoma and other human cancers
6. Refined chromosomal localization of the putative tumour suppressor gene TP73
7. p73 is a human p53-related protein that can induce apoptosis
8. The tyrosine kinase c-Abl regulates p73 in apoptotic response to cisplatin-induced DNA damage
9. p73 at chromosome 1p36.3 is lost in advanced stage neuroblastomas but its mutation is infrequent
10. Infrequent somatic mutations of the p73 gene in various human cancers
11. A simple salting out procedure for extracting DNA from human nucleated cells
12. Minimal residual disease after allogeneic bone marrow transplantation for chronic myeloid leukaemia in first chronic phase: Correlations with acute graft-versus-host disease and relapse
13. Genomic organisation and mutation analysis of p73 in oligodendrogliomas with chromosome 1p-arm deletions
14. Two distinct deleted regions on the short arm of chromosome 1 in neuroblastoma
15. Loss of heterozygosity at chromosome 9p21 in primary neuroblastomas: Evidence for two deleted regions
16. PCR assay for chromosome 1p deletion in small neuroblastoma samples
17. Expression of N-myc in teratocarcinoma stem cells and mouse embryos
18. Revision of the international criteria for neuroblastoma diagnosis, staging and response to treatment
19. RNA structure and the regulation of gene expression
20. Loss of p73 gene expression in leukaemia/lymphomas due to hypermethylation
21. Activation of p73 silent allele in lung cancer