HIV time hierarchy: Winning the war while, loosing all the battles

Physica A: Statistical Mechanics and its Applications

Volumn 289, Issue 1-2, 2001, Pages 178-190

  Hershberg, Uri ^a   Louzoun, Yoram ^a   Atlan, Henri ^b   Solomon, Sorin ^a  

^a HEBREW UNIVERSITY OF JERUSALEM   (Israel)

^b HADASSAH HEBREW UNIVERSITY MEDICAL CENTER   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; COMPUTER SIMULATION; DISEASES; EPIDEMIOLOGY; IMMUNOLOGY; MONTE CARLO METHODS; VIRUSES;

ACQUIRED IMMUNE DEFICIENCY SYNDROME (AIDS); HUMAN IMMUNO VIRUS (HIV);

ANTIGEN-ANTIBODY REACTIONS;

EID: 0035149343     PISSN: 03784371     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-4371(00)00466-0     Document Type: Article

References (25)

1. G. Pantaleo, C. Graziozi, A. Fauci, The immunopathogenesis of human-immunodeficiency-virus infection, N. Engl. J. Med. 328 (1993) 327.
2. R.M. Zorzenon dos Santos, Immune responses: getting close to experimental results with cellular automata models, in: D. Stauffer (Ed.), Annual Review of Computational Physics VI, 1999, pp. 159-202, notice especially Fig. 13.
3. R.M. Zorzenon dos Santos, S.C. Coutinho, On the dynamics of the evolution of HIV infection, cond-mat/0008081.
4. R.E. Hurlbert, http://www.wsu.edu:8080/~hurlbert/pages/Chap16.html#STD_intro
5. Y. Louzoun, I. Cohen, H. Atlan, Destruction of CD4 T lymphocytes alone cannot account for their long-term decrease in AIDS, PNAS, (2000), submitted math-0008052.
6. A.S. Pearlson, Modeling the interaction of HIV with the immune system, in: C. Castilo-Chavez (Ed.), Mathematical and Statistical Approaches to AIDS Epidemiology, Lecture Notes in Biomathematics, Vol. 83, 1989, pp. 350-370.
7. D.E. Kirschner, R. Mehr, A.S. Perelson, Role of the thymus in pediatric HIV-1 infection, J. AIDS Retroviro. 18 (1998) 95-109.
8. M.A. Nowak, C.R.M. Bangham, Population dynamics of immune response to persistent viruses, Science 272 (1996) 74-79.
9. J.D. Roberts, K. Benbenk, T.A. Kunkel, The accuracy of reverse transcriptase from HIV-1, Science 242 (1988) 1171-1173.
10. Y. Takeuchi, T. Nagumo, H. Hoshino, Low fidelity of cell-free DNA synthesis by reverse transcriptase of human immunodeficiency virus, J. Virol. 62 (1989) 3900-3902.
11. T.-W. Chun, L. Carruth, D. Finzi et al., Quantification of latent tissue reservoirs and total body viral load in HIV infection, Nature 387 (1997) 183-187.
12. M.A. Nowak, A.J. McMichael, How HIV defeats the immune system, Sci. Am. 273 (1995) 58-65.
13. R.M. Berry, M.A. Nowak, A role for defective mutants in HIV pathogenesis, J. Theoret. Biol. 171 (1994).
14. M.A. Nowak, R.M. Anderson, A.R. McLean, T.F. Wolfs, J. Goudsmit, R.M. May, Antigenic diversity thresholds and the development of AIDS, Science 254 (1991) 941, 963-969.
15. M.A. Nowak, R.M. May, R.E. Philips et al., Antigenic oscillations and shifting immunodomminance in HIV-1 infections, Nature 375 (1995) 606-611.
16. S. Bonhoeffer, E.C. Holmes, M.A. Nowak, Causes of HIV diversity, Nature 376 (1995) 125.
17. D. Klatzman, E. Champagne, S. Camaret et al., T-lymphocyte T4 molecule acts as receptor for human retrovirus LAV, Nature 312 (1984) 767-768.
18. S. Solomon, The microscopic representation of complex macroscopic phenomena: "Critical slowing down - A blessing in disguise", in: D. Stauffer (Ed.), Annual Reviews of Computational Physics II, World Scientific, Singapore, 1995, pp. 243-294.
19. N. Persky, I. Kanter, S. Solomon, Cluster dynamics for randomly frustrated systems with finite connectivity, Phys. Rev. E 53 (1996) 1212, cond-mat/9604112.
20. N. Persky, S. Solomon, Collective degrees of freedom and multiscale dynamics in spin glasses, Phys. Rev. E 54 (1996) 4399, cond-mat/9603056.
21. I. Stenhill, S. Solomon, K. Wolowelsk, Dynamical algebraic multi-grid simulations of free fields on random triangulated surfaces, Comput. Phys. Commun. 83 (1994) 23-29.
22. E.L. Delwart, H.W. Sheppard, B.D. Walker, J. Goudsmit, J.I. Mulins, Human immunodeficiency virus type 1 evolution in vivo tracked by DNA hetroduplex mobility assays, J. Virol. 68 (1994) 6672-6683.
23. G. Pantaleo, J.F. Demarest, T. Schacker et al, The qualitative nature of primary immune response to HIV infection is a prognosticator of disease progression independant of initial level of plasma viremia, PNAS 94 (1997) 254-258.
24. J. Levy, J. Shimabukuro, T. McHugh, C. Casavant, D. Stites, L. Oshiro, AIDS associated retroviruses (ARV) can productively infect other cells besides human T helper cells, Viriology 147 (1985) 441-448.
25. B. Tindall, M. Hing, P. Edwards, T. Barnes, A. Mackie, D.A. Cooper, Severe clinical manifestations of primary HIV infection, AIDS 3 (1989) 747-749.