Isodicentric 7p, idic(7)(q11.2), in acute myeloid leukemia associated with older age and favorable response to induction chemotherapy: A new clinical entity?

Genes Chromosomes and Cancer

Volumn 30, Issue 3, 2001, Pages 261-266

  Johansson, Bertil ^a   Axelsson, Per ^a   Billstrm, Rolf ^a   Strmbeck, Bodil ^b   Arheden, Kristina ^d   Olofsson, Tor ^a   Cervin, Anneli ^b   Adriansson, Magnus ^a   Tanke, Hans J ^b,c,d   Mitelman, Felix ^a   Fioretos, Thoas ^c  

^a LUND UNIVERSITY HOSPITAL   (Sweden)

^b HELSINGBORG HOSPITAL   (Sweden)

^c Kalmar Hospital   (Sweden)

^d LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CYTARABINE; IDARUBICIN; TIOGUANINE;

ACUTE GRANULOCYTIC LEUKEMIA; AGED; ARTICLE; CANCER CHEMOTHERAPY; CANCER REGRESSION; CASE REPORT; CENTROMERE; CHROMOSOME 7P; CHROMOSOME ABERRATION; CHROMOSOME G BAND; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; GENE REARRANGEMENT; HUMAN; ISOCHROMOSOME; MALE; PRIORITY JOURNAL; PROGNOSIS;

AGED; AGED, 80 AND OVER; AGING; ANTIMETABOLITES, ANTINEOPLASTIC; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CHROMOSOME BANDING; CHROMOSOMES, HUMAN, PAIR 7; CYTARABINE; FEMALE; HUMANS; IDARUBICIN; IN SITU HYBRIDIZATION, FLUORESCENCE; ISOCHROMOSOMES; LEUKEMIA, MYELOCYTIC, ACUTE; LEUKEMIA, MYELOMONOCYTIC, ACUTE; MALE; REMISSION INDUCTION; THIOGUANINE;

EID: 0035147020     PISSN: 10452257     EISSN: None     Source Type: Journal    
DOI: 10.1002/1098-2264(2000)9999:9999<::AID-GCC1087>3.0.CO;2-A     Document Type: Article

References (32)

1. TEL-AML1 fusion in acute lymphoblastic leukaemia of adults
2. Acute myeloid leukemia and clonal chromosomal aberrations. Relation to past exposure to organic solvents
3. Deletions of CDKN1B and ETV6 in acute myeloid leukemia and myelodysplastic syndromes without cytogenetic evidence of 12p abnormalities
4. Trisomy 13 in acute leukemia
5. Isochromosome 17q in Ph1-negative leukemia: A clinical, cytogenetic, and molecular study
6. Nineteen cases of the t(1;22)(p13;q13) acute megakaryoblastic leukaemia of infants/children and a review of 39 cases: Report from a t(1;22) study group
7. A case of isodicentric 7p as sole abnormality in a patient with acute myeloid leukemia
8. Therapy of untreated acute myeloid leukemia in the elderly: Remission-induction using a non-cytarabine-containing regimen of mitoxantrone plus etoposide
9. Cytogenetics and their prognostic value in de novo acute myeloid leukaemia: A report on 283 cases
10. Isochromosome 17q in blast crisis of chronic myeloid leukemia and in other hematologic malignancies is the result of clustered breakpoints in 17p11 and is nor associated with coding TP53 mutations
11. Overview of association between chromosome pattern and cell morphology, age, sex, and race
12. The importance of diagnostic cytogenetics on outcome in AML: Analysis of 1,612 patients entered into the MRC AML 10 trial
13. Characterization of chromosome aberrations in salivary gland tumors by fluorescence in situ hybridization (FISH), including multicolor COBRA-FISH
14. Cytogenetics of secondary myelodysplasia (sMDS) and acute nonlymphocytic leukemia (sANLL)
15. Geographic heterogeneity of neoplasia-associated chromosome aberrations
16. Primary vs. secondary neoplasia-associated chromosomal abnormalities: Balanced rearrangements vs. genomic imbalances?
17. Hematologic malignancies with t(4;11)(q21;q23): A cytogenetic, morphologic, immunophenotypic and clinical study of 183 cases
18. Acute myeloid leukemia in the elderly: Assessment of multidrug resistance (MDR1) and cytogenetics distinguishes biologic subgroups with remarkably distinct responses to standard chemotherapy - A Southwest Oncology Group study
19. Abnormalities of chromosomes 8, 11, 14, and X in T-prolymphocytic leukemia studied by fluorescence in situ hybridization
20. A single-center population-based consecutive series of 1500 cytogenetically investigated adult hematological malignancies: Karyotypic features in relation to morphology, age and gender
21. Survival time in a population-based consecutive series of adult acute myeloid leukemia: The prognostic impact of karyotype during the time period 1976-1993
22. Age- and gender-related heterogeneity of cancer chromosome aberrations
23. Isochromosomes in neoplasia
24. A breakpoint map of recurrent chromosomal rearrangements in human neoplasia
25. The balanced and the unbalanced chromosome aberrations of acute myeloid leukemia may develop in different ways and may contribute differently to malignant transformation
26. New strategy for multi-colour fluorescence in situ hybridization: COBRA - COmbined Binary RAtio Labelling
27. Cytogenetic abnormalities in the myelodysplastic syndromes and occupational or environmental exposure
28. Molecular definition of breakpoints associated with human Xq isochromosomes: Implications for mechanisms of formation