Chronic treatment with reboxetine by osmotic pumps facilitates its effect on extracellular noradrenaline and may desensitize α2-adrenoceptors in the prefrontal cortex

British Journal of Pharmacology

Volumn 132, Issue 1, 2001, Pages 183-188

  Invernizzi, R W ^a   Parini, S ^a   Sacchetti, G ^a   Fracasso, C ^a   Caccia, S ^a   Annoni, K ^b   Samanin, R ^a  

^a MARIO NEGRI INSTITUTE FOR PHARMACOLOGICAL RESEARCH   (Italy)

^b PFIZER INC   (United States)

Author keywords

Chronic treatment; Dopamine; Microdialysis; Noradrenaline; Prefrontal cortex; Reboxetine; Serotonin

Indexed keywords

ALPHA 2 ADRENERGIC RECEPTOR; CLONIDINE; DOPAMINE; NORADRENALIN; REBOXETINE; SEROTONIN;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DESENSITIZATION; DOSE RESPONSE; DRUG BLOOD LEVEL; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LONG TERM CARE; MALE; MICRODIALYSIS; NONHUMAN; OSMOTIC PUMP; PREFRONTAL CORTEX; PRIORITY JOURNAL; RAT;

EID: 0035146024     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0703821     Document Type: Article

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