All angiogenesis is not the same: Distinct patterns of response to antiangiogenic therapy in experimental neuroblastoma and wilms tumor

Journal of Pediatric Surgery

Volumn 36, Issue 2, 2001, Pages 287-290

  Kim, Eugene ^a   Moore, James ^a   Huang, Jianzhong ^a   Soffer, Samuel ^a   Manley, Christina A ^a   O'Toole, Kathleen ^a   Middlesworth, William ^a   Stolar, Charles J ^a   Kandel, Jessica J ^a   Yamashiro, Darrell J ^a,b  

^a College of Physicians and Surgeons ^*  (United States)

^b CHILDREN S HOSPITAL OF NEW YORK   (United States)

Author keywords

Angiogenesis; Antiangiogenic therapy; Neuroblastoma; Vascular endothelial growth factor; Wilms tumor

Indexed keywords

ANGIOGENESIS INHIBITOR; VASCULOTROPIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN SPECIFICITY; CONFERENCE PAPER; CONTROLLED STUDY; DRUG EFFECT; FLUORESCENCE ANGIOGRAPHY; GROWTH INHIBITION; HUMAN; HUMAN CELL; KIDNEY PARENCHYMA; MOUSE; NEOVASCULARIZATION (PATHOLOGY); NEPHROBLASTOMA; NEUROBLASTOMA; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; TUMOR GROWTH; XENOGRAFT;

EID: 0035144453     PISSN: 00223468     EISSN: None     Source Type: Journal    
DOI: 10.1053/jpsu.2001.20691     Document Type: Conference Paper

References (8)

1. Vascular endothelial growth factor is a secreted angiogenic mitogen
2. Vascular permeability factor (VPF, VEGF) in tumor biology
3. Neovasculature induced by vascular endothelial growth factor is fenestrated
4. Antiangiogenic therapy targeting the tyrosine kinase receptor for vascular endothelial growth factor receptor inhibits the growth of colon cancer liver metastasis and induces tumor and endothelial cell apoptosis
5. Neutralizing antivascular endothelial growth factor antibody inhibits further growth of established prostate cancer and metastases in a pre-clinical model
6. Anti-VEGF antibody suppresses primary tumor growth and metastasis in an experimental model of Wilms tumor
7. Suppression of primary tumor growth in a mouse model of human neuroblastoma
8. Vessel cooption, regression, and growth in tumors mediated by angiopoietins and VEGF