The effects of pain on opioid tolerance: How do we resolve the controversy?

Pharmacological Reviews

Volumn 48, Issue 3, 1996, Pages 403-412

  Gutstein, Howard B ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOBUTYRIC ACID RECEPTOR STIMULATING AGENT; CHOLECYSTOKININ; FORMALDEHYDE; GLUCOCORTICOID; MORPHINE; MUSCIMOL; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; OPIATE;

ANALGESIA; ANALGESIC ACTIVITY; CHRONIC PAIN; DRUG EFFICACY; DRUG THERAPY; DRUG TOLERANCE; ETIOLOGY; HUMAN; HYPERALGESIA; HYPOALGESIA; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; NOCICEPTIVE STIMULATION; NONHUMAN; PRIORITY JOURNAL; REVIEW; WITHDRAWAL SYNDROME;

ANALGESICS, OPIOID; DRUG TOLERANCE; HUMANS; PAIN;

EID: 0029812270     PISSN: 00316997     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (60)

1. ABBOTT, F. V., FRANKLIN, K. B. J., LUDWICK, R. J., AND MELZACK, R.: Apparent lack of tolerance in the formalin test suggests different mechanisms for morphine analgesia in different types of pain. Pharmacol. Biochem. Behav. 15: 637-640, 1981.
2. ABBOTT, F. V., MELZACK, R., AND LEBER, B. F.: Morphine analgesia and tolerance the tail-flick and formalin tests: dose-response relationships. Pharmacol. Biochem. Behav. 17: 1213-1219, 1982.
3. AKIL, H., MADDEN, J., PATRICK, R., AND BARCHAS, J.: Stress-induced increased in endogenous opiate peptides: concurrent analgesia and its partial reversal by naloxone. In Opiates and Endogenous Opioid Peptides, ed. by H. Kosterlitz, pp. 63-70, Elsevier, Amsterdam, 1976.
4. APPELBAUM, B., AND HOLTZMAN, S.: Characterization of stress-induced potentiation of opioid effects in the rat. J. Pharmacol. Exp. Ther. 231: 555-565, 1984.
5. BAKER, T. B., AND TIFFANY, S. T.: Morphine tolerance as habituation. Psychol. Rev. 92: 78-108, 1985.
6. BASBAUM, A. I.: Insights into the development of opioid tolerance. Pain 61: 349-352, 1995.
7. BENNETT, G. J., AND XIE, Y. K.: A peripheral mononeuropathy in rat that produces disorders of pain sensation like those seen in man. Pain 33: 87-107, 1988.
8. CODERRE, T. J., KATZ, J., VACCARINO, A. L., AND MELZACK, R.: Contribution of central neuroplasticity to pathological pain: review of clinical and experimental evidence. Pain 52: 259-285, 1993.
9. COLPAERT, F. C.: Long-term suppression of pain by narcotic drugs in the absence of tolerance development. Arch. Int. Pharmacodyn. 236: 293-295, 1978.
10. COLPAERT, F. C., NIEMEGEERS, C. J. E., AND JANSSEN, P. A. J.: Nociceptive stimulation prevents development of tolerance to narcotic analgesia. Eur. J. Pharmacol. 49: 335-336, 1978.
11. COLPAERT, F. C., NIEMEGEERS, C. J. E., JANSSEN, P. A. J., AND MAROLI, A. N.: The effects of prior fentanyl administration and of pain on fentanyl analgesia: tolerance to and enhancement of narcotic analgesia. J. Pharmacol. Exp. Ther. 213: 418-424, 1980.
12. COLPAERT, F. C. System theory of pain and of opiate analgesia: no tolerance to opiates. Pharmacol. Rev. 48: 355-402, 1996.
13. CONNELL, B. J., BARNES, J. C., BLATT, T., AND TASKER, R.: Rapid development of tolerance to morphine in the formalin test. NeuroReport 5: 817-820, 1994.
14. COX, B. M.: Molecular and cellular mechanisms in opioid tolerance. In Towards a New Pharmacotherapy of Pain, ed. by A. I. Basbaum and J. M. Besson, pp. 137-155, John Wiley and Sons, New York, 1991.
15. COX, B. M., AND WERLING, L. L.: Opioid tolerance and dependence. In The Biological Bases of Drug Tolerance and Dependence, ed. by J. Pratt, pp. 199-229, Harcourt Brace Jovanovich, New York, 1991.
16. DUBNER, R.: Methods of assessing pain in animals. In Textbook of Pain, ed. by P. D. Wall and R. Melzack, pp. 293-302, Churchill Livingstone, London, 1994.
17. FIELDS, H. L., EMSON, P. C., LEIGH, B. K., GILBERT, R. F., AND IVERSEN, L. L.: Multiple opiate receptor sites on primary afferent fibres. Nature (Lond.) 284: 351-353, 1980.
18. GRISEL, J. E., WIERTELAK, E. P., WATKINS, L. R., AND MAIER, S. F.: Route of morphine administration modulates conditioned analgesic tolerance and hyperalgesia. Pharmacol. Biochem. Behav. 49: 1029-1035, 1994.
19. GUTSTEIN, H., TRUJILLO, K, AND AKIL, H.: Chronic pain decreases morphine analgesic potency in rats. In 7th World Congress on Pain, abstract no. A-1236, IASP Publications: Paris, 1993.
20. GUTSTEIN, H. B., AND TRUJILLO, K. A.: MK-801 inhibits the development of morphine tolerance at spinal sites. Brain Res. 626: 332-334, 1993.
21. GUTSTEIN, H. B., TRUJILLO, K. A., AND AKIL, H.: Does chronic nociceptive stimulation alter the development of morphine tolerance? Brain Res. 680: 173-179, 1995.
22. HOUDE, R. W., WALLENSTEIN, S. L., AND BEAVER, W. T.: Evaluation of analgesics in patients with cancer pain. In Clinical Pharmacology, ed. by L. Lasagna, vol. 1, pp. 59-98, Pergamon, Oxford, 1966.
23. KAYAN, S., WOODS, L. A., AND MITCHELL, C. L.: Experience as a factor in the development of tolerance to the analgesic effect of morphine. Eur. J. Pharmacol. 6: 333-339, 1969.
24. KAYSER, V., AND GIULBAUD, G.: Can tolerance to morphine be induced in arthritic rats? Brain Res. 334: 335-338, 1985.
25. KAYSER, V., LEE, S. H., AND GIULBAUD, G.: Evidence for a peripheral component in the enhanced nociceptive effect of a low dose of systemic morphine in rats with peripheral mononeuropathy. Neuroscience 64: 537-545, 1995.
26. MACLENNAN, A., DRUGAN, R., HYSON, R., AND MAIER, S.: Corticosterone: a critical factor in an opioid form of stress-induced analgesia. Science (Wash. DC) 215: 1530-1532, 1982.
27. MADDEN, J., AKIL, H., PATRICK, R., AND BARCHAS, J.: Stress-induced parallel changes in central opioid levels and pan responsiveness in the rat. Nature (Lond.) 265: 358-360, 1977.
28. MAO, J., PRICE, D. D., AND MAYER, D. J.: Thermal hyperalgesia in association with the development of morphine tolerance in rats: roles of excitatory amino acid receptors and protein kinase C. J. Neuroscience 14: 2301-2312, 1994.
29. MAO, J., PRICE, D. D., AND MAYER, D. J.: Experimental mononeuropathy reduces the antinociceptive effects of morphine: Implications for common intracellular mechanisms involved in morphine tolerance and neuropathic pain. Pain 61: 353-364, 1995a.
30. MAO, J., PRICE, D. D., AND MAYER, D. J.: Mechanisms of hyperalgesia and morphine tolerance: a current view of their possible interactions. Pain 62: 259-274, 1995b.
31. MONACO, S., GEHRMANN, J., RAIVICH, G., AND KREUTZBERG, G. W.: MHC-positive, ramified macrophages in the normal and injured rat nervous system. J. Neurocytology 21: 623-634, 1992.
32. NESTLER, E. J.: Molecular mechanisms of drug addiction. J. Neuroscience 12: 2439-2450, 1992.
33. 3H-nitrencipine binding to synaptic membranes: similarity with morphine tolerance. Naunyn-Schmiedeberg's Arch. Pharmacol. 341: 123-127, 1990.
34. ONOFRIO, B. M., AND YAKSH, T. L.: Long-term pain relief produced by intrathecal morphine infusion in 53 patients. J. Neurosurgery 72: 200-209, 1990.
35. PORTENOY, R. K., AND FOLEY, K. M.: Chronic use of opioid analgesics in non-malignant pain: report of 38 cases. Pain 25: 171-186, 1986.
36. PORTENOY, R. K., MOULIN, D. E., ROGERS, A., INTURRISI, C. E., AND FOLEY, K. M.: IV infusion of opioids for cancer pain: clinical review and guidelines for use. Cancer Treat. Rep. 70: 575-581, 1986.
37. RAHMAN, A. F. M., TAKAHASHI, M., AND KANETO, H.: Involvement of pain associated anxiety in the development of morphine tolerance in formalin treated mice. Jpn. J. Pharmacol. 65: 313-317, 1994.
38. RAHMAN, A. F. M., TAKAHASHI, M., AND KANETO, H.: Role of GABAergic systems in the development of morphine tolerance in formalin treated mice. Jpn. J. Pharmacol. 68: 207-211, 1995.
39. REINSCHEID, R. K., NOTHACKER, H.-P., BOURSON, A., ARDATI, A., HENNINGSEN, R. A., BUNZOW, J. R., GRANDY, D. K., LANGEN, H., MONSMA, F. J., AND CIVELLI, O.: Orphanin FQ: a neuropeptide that activates an opioidlike G protein-coupled receptor. Science (Wash DC) 270: 792-794, 1995.
40. ROTHMAN, R. B.: A review of the role of anti-opioid peptides in morphine tolerance and dependence. Synapse 12: 129-138, 1992.
41. SELTZER, Z., DUBNER, R., AND SHIR, Y.: A novel behavioral model of neuropathic pain disorders produced in rats by partial sciatic nerve injury. Pain 43: 205-218, 1990.
42. SHERMAN, J. E., PROCTOR, C., AND STRUB, H.: Prior hot plate exposure enhances morphine analgesia in tolerant and drug-naive rats. Pharmacol. Biochem. Behav. 17: 229-232, 1981.
43. STEIN, C.: Peripheral mechanisms of opioid analgesia. Anesth. Analg. 76: 182-191, 1993.
44. STEIN, C.: The control of pain in peripheral tissue by opioids. N. Engl. J. Med. 332: 1685-1690, 1995.
45. STEIN, C., COMISEL, K., HAIMERL, E., YASSOURIDIS, A., LEHRBERGER, K., HERZ, A., AND PETER, K.: Analgesic effect of intraarticular morphine after arthroscopic knee surgery. N. Engl. J. Med. 325: 1123-1126, 1991.
46. STEIN, C., HASSAN, A. H. S., LEHRBERGER, K., GIEFING, J., AND YASSOURIDIS, A.: Local analgesic effect of endogenous opioid peptides. Lancet 342: 321-324, 1993.
47. SUTTON, L., FLESHNER, M., MAZZEO, R., MAIER, S., AND WATKINS, L.: A permissive role of corticosterone in an opioid form of stress-induced analgesia: blockade of opiate analgesia is not due to stress-induced hormone release. Brain Res. 663: 19-29, 1994.
48. TAKAHASHI, M., DEGUCHI, Y., AND KANETO, H.: Blockade of the development of analgesic tolerance to morphine by concurrent treatment with opioid- but not non-opioid-mediated stress in mice. Jpn. J. Pharmacol. 46: 1-5, 1988.
49. TAKAHASHI, M., AND KANETO, H.: Footshock- and psychological-stress prevent the development of tolerance to spinal but not supraspinal morphine. Jpn. J. Pharmacol. 56: 121-126, 1991.
50. TAKAHASHI, M., SUGIMACHI, K., AND KANETO, H.: Role of adrenal glucocorticoids in the blockade of the development of analgesic tolerance to morphine by footshock stress exposure in mice. Jpn. J. Pharmacol. 51: 329-336, 1989.
51. TERMAN, G. W., SHAVIT, Y., LEWIS, J. W., CANNON, J. T., AND LIEBESKIND, J. C.: Intrinsic mechanisms of pain inhibition: activation by stress. Science (Wash. DC) 226: 1270-1277, 1984.
52. TRUJILLO, K., AND AKIL, H.: Excitatory amino acids and drugs of abuse: a role for N-methyl-D-aspartate receptors in drug tolerance, sensitization and physical dependence. Drug Alcohol Depend. 38: 139-154, 1994.
53. TRUJILLO, K. A., AND AKIL, H.: Opiate tolerance and dependence: recent findings and synthesis. New Biologist 3: 915-923, 1991.
54. VACCARINO, A. L., AND COURET JR., L. C.: Relationship between hypothalamic-pituitary-adrenal activity and blockade of tolerance to morphine analgesia by pain: a strain comparison. Pain 63: 385-389, 1995.
55. VACCARINO, A. L., MAREK, P., KEST, B., BEN-ELIYAHU, S., LELAND C. COURET, J., KAO, B., AND LIEBSKIND, J. C.: Morphine fails to produce tolerance when administered in the presence of formalin pain in rats. Brain Res. 627: 287-290, 1993.
56. WALL, P. D., DEVOR, M., INBAL, R., SCADDING, J. W., SCHONFELD, D., SELTZER, Z., AND TOMKIEWICZ, M. M.: Autotomy following peripheral nerve lesions: experimental anaesthesia dolorosa. Pain 7: 103-113, 1979.
57. WATKINS, L. R., AND MAYER, D. J.: Organization of endogenous opiate and nonopiate pain control systems. Science (Wash. DC) 216: 1185-1192, 1982.
58. WIERTELAK, E. P., FURNESS, L. E., HORAN, R., MARTINEZ, J., MAIER, S. F., AND WATKINS, L. R.: Subcutaneous formalin produces centrifugal hyperalgesia at a non-injected site via the NMDA-nitric oxide cascade. Brain Res. 649: 19-26, 1994.
59. WIEKTELAK, E. P., MAIER, S. F., AND WATKINS, L. R.: Cholecystokinin antianalgesia: safety cues abolish morphine analgesia. Science (Wash. DC) 256: 830-833, 1992.
60. WOOLF, C. J.: The dorsal horn: state-dependent sensory processing and the generation of pain. In Textbook of Pain, ed. by P. D. Wall and R. Melzack, pp. 101-112, Churchill Livingstone, London, 1994.