Development and characterization of T cell leukemia cell lines established from SCL/LMO1 double transgenic mice

Leukemia

Volumn 15, Issue 1, 2001, Pages 141-147

  Chervinsky, D S ^a   Lam, D H ^a,b   Zhao, X F ^a   Melman, M P ^b   Aplan, P D ^b  

^a ROSWELL PARK CANCER INSTITUTE   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Cell line; Leukemia; LMO1; Mouse; SCL

Indexed keywords

GENE PRODUCT; HELIX LOOP HELIX PROTEIN; LIM PROTEIN;

ACUTE LYMPHOBLASTIC LEUKEMIA; ANEUPLOIDY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER GROWTH; CELL DENSITY; CELL IMMORTALIZATION; CELL PROLIFERATION; CONTROLLED STUDY; DIPLOIDY; GENE ACTIVATION; IN VITRO STUDY; LEUKEMIA CELL LINE; MOUSE; NONHUMAN; PRIORITY JOURNAL; STROMA CELL; T CELL LEUKEMIA; TRANSGENIC MOUSE;

EID: 0035140870     PISSN: 08876924     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.leu.2401997     Document Type: Article

References (23)

1. Human hematopoietic cell lines: A progress report
2. Guidelines for the characterization and publication of human malignant hemotopoietic cell lines
3. False human hematopoietic cell lines: Cross-contaminations and misinterpretations
4. Does activation of the TAL1 gene occur in a majority of patients with T-cell acute lymphoblastic leukemia? A Pediatric Oncology Group study
5. The rhombotin family of cysteine-rich LIM-domain oncogenes: Distinct members are involved in T-cell translocations to human chromosomes 11p15 and 11p13
6. The oncogenic LIM protein Rbtn2 causes thymic developmental aberrations that precede malignancy in transgenic mice
7. Protein dimerization between Lmo2 (Rbtn2) and Tal1 alters thymocyte development and potentiates T cell tumorigenesis in transgenic mice
8. An scl gene product lacking the transactivation domain induces boy abnormalities and cooperates with LMO1 to generate T-cell malignancies in transgenic mice
9. Disordered T-cell development and T-cell malignancies in SCL LMO1 double-transgenic mice: Parallels with E2A-deficient mice
10. E2A deficiency leads to abnormalities in alpha-beta T-cell development and to rapid development of T-cell lymphomas
11. Positive and negative transcriptional control by the TAL1 helix-loop-helix protein
12. The Tal1 oncoprotein inhibits E47-mediated transcription - Mechanism of inhibition
13. The E2A and tal-1 helix-loop-helix proteins associate in vivo and are modulated by ld proteins during interleukin 6-induced myeloid differentiation
14. High incidence of T-cell tumors in E2A-null mice and E2A/ld1 double-knockout mice
15. The SCL gene is formed from a transcriptionally complex locus
16. Thymic overexpression of Ttg-1 in transgenic mice results in T-ceell acute lymphoblastic leukemia/lymphoma
17. Cloning and characterization of a murine SIL gene
18. The t(11;14)(p15;q11) in a T-cell acute lymphoblastic leukemia cell line activates multiple transcripts, including Ttg1, a gene encoding a potential zinc finger protein
19. Rescue of T cell-specific V(D)J recombination in SCID mice by DNA-damaging agents
20. Reversible tumorigenesis by MYC in hematopoietic lineages
21. Transgenic models of a lymphoid neoplasia and development of a pan-hematopoietic vector
22. Role of the cyclin-dependent kinase inhibitors in the development of cancer
23. Review of alterations of the cyclin-dependent kinase inhibitor of INK4 family genes p15, p16, p18, and p19 in human leukemia lymphoma cells