Effects of droloxifene on apoptosis and Bax, Bcl-2 protein expression of luteal cells in pseudopregnant rats

Acta Pharmacologica Sinica

Volumn 22, Issue 2, 2001, Pages 155-162

  Leng, Y ^a   Feng, Y ^a   Cao, L ^a   Gu, Z P ^a  

^a Chinese Academy of Sciences   (China)

Author keywords

Apoptosis; Corpus luteum; Droloxifene; Proteins; Pseudopregnancy; Rats

Indexed keywords

DROLOXIFENE; PROTEIN BAX; PROTEIN BCL 2; 3-HYDROXYTAMOXIFEN; ANTIESTROGEN; DRUG DERIVATIVE; ONCOPROTEIN; PROTO ONCOGENE PROTEINS; PROTO ONCOGENE PROTEINS C BCL 2; TAMOXIFEN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; CORPUS LUTEUM; FEMALE; IMMUNOHISTOCHEMISTRY; LUTEAL CELL; LUTEOLYSIS; MALE; NICK END LABELING; NONHUMAN; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PSEUDOPREGNANCY; RAT; ANIMAL; BIOSYNTHESIS; CYTOLOGY; DRUG EFFECT; METABOLISM; RAT STRAIN;

ANIMAL; APOPTOSIS; ESTROGEN ANTAGONISTS; FEMALE; LUTEAL CELLS; MALE; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; PSEUDOPREGNANCY; RATS; RATS, SPRAGUE-DAWLEY; SUPPORT, NON-U.S. GOV'T; TAMOXIFEN;

EID: 0035137294     PISSN: 02539756     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (22)

1. Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetic
2. Social controls on cell survival and cell death
3. Occurrence of deoxyribonucleic acid fragmentation during prolactin-induced structural luteolysis in cycling rats
4. Apoptosis during luteal regression in cattle
5. Evaluation of growth, cell proliferation, and cell death in bovine corpora lutea throughout the estrus cycles
6. Cell proliferation and apoptosis during development and aging of the rabbit corpus luteum
7. Internucleosomal DNA fragmentation in ovine luteal tissue associated with luteolysis: In vivo and in vitro analyse
8. Cell death during luteal regression in the marmoset monkey (Callithrix jacchus)
9. Apoptosis of human corpora lutea during cyclic luteal regression and early pregnancy
10. Programmed cell death in human ovary is a function of follicle and corpus luteum status
11. Apoptosis: Basic concepts and potential significance in human cancer
12. Increased bax and interleukin-1β-converting enzyme messenger ribonucleic acid levels coincide with apoptosis in the bovine corpus luteum during structural regression
13. Production of the proto-oncogene Bax does not vary with changing in luteal function in women
14. Immunolocalization of bcl-2 in the human corpus luteum
15. Pharmacologic and biologic properties of droloxifene, a new antiestrogen
16. Effects of anordrin, droloxifene, nomegestrol, and mifepristone on cultured rat luteal cell apoptosis
17. Experimental pharmacological studies on the male antifertility agent α-chlorohydrin and its analogues
18. Mechanisms controlling corpus luteum function in sheep, cows, nonhuman primates, and women especially in relation to the time of luteolysis
19. Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death
20. Mcl-1, a gene expressed in programmed myloid cell differentiation, has sequence similarity to bcl-2
21. Cloning of a bcl-2 homologue by interaction with adenovirus E1B 19K
22. Bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death