Suppression of cell proliferation by tissue plasminogen activator during the early phase after balloon injury minimizes intimal hyperplasia in hypercholesterolemic rabbits

Journal of Cardiovascular Pharmacology

Volumn 37, Issue 2, 2001, Pages 155-162

  Kanamasa, Ken ^a   Otani, Narutaka ^a   Ishida, Norihiro ^a   Inoue, Yoshikazu ^a   Ikeda, Akiko ^a   Morii, Hideki ^a   Naito, Norikatsu ^a   Hayashi, Takahiro ^a   Ishikawa, Kinji ^a   Miyazawa, Masaaki ^a  

^a KINKI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Balloon injury; Intimal hyperplasia; Restenosis; Thrombus; Tissue plasminogen activator

Indexed keywords

ALTEPLASE; CYCLINE; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERY INJURY; ARTERY INTIMA PROLIFERATION; ARTICLE; BALLOON CATHETER; CELL PROLIFERATION; CONTROLLED STUDY; FEMALE; HEMODYNAMICS; HYPERCHOLESTEROLEMIA; ILIAC ARTERY; IMMUNOHISTOCHEMISTRY; MALE; NONHUMAN; PRIORITY JOURNAL; RABBIT; RESTENOSIS; THROMBUS;

ANIMALS; CELL DIVISION; FEMALE; HEMODYNAMIC PROCESSES; HYPERCHOLESTEROLEMIA; HYPERPLASIA; IMMUNOHISTOCHEMISTRY; MALE; MUSCLE, SMOOTH, VASCULAR; PLASMINOGEN ACTIVATOR INHIBITOR 1; PROLIFERATING CELL NUCLEAR ANTIGEN; RABBITS; RECOMBINANT PROTEINS; TISSUE PLASMINOGEN ACTIVATOR; TRANSFORMING GROWTH FACTOR BETA;

EID: 0035137125     PISSN: 01602446     EISSN: None     Source Type: Journal    
DOI: 10.1097/00005344-200102000-00003     Document Type: Article

References (33)

1. Angioscopic observation of the coronary luminal changes induced by percutaneous transluminal coronary angioplasty
2. Angioscopic prediction of successful dilatation and of restenosis in percutaneous transluminal coronary angioplasty: Significance of yellow plaque
3. A paradigm for restenosis based on cell biology: Clues for the development of new preventive therapies
4. The restenosis paradigm revisited: An alternative proposal for cellular mechanisms
5. The pathogenesis of atherosclerosis - An update
6. Vascular smooth muscle cells from injured rat aortas display elevated matrix production associated with transforming growth factor-β activity
7. Hyperlipidemia and coronary disease. Correction of the increased thrombogenic potential with cholesterol reduction
8. New mutant rabbit strain with hypercholesterolemia and atherosclerotic lesions produced by serial inbreeding
9. Recombinant tissue plasminogen activator prevents intimal hyperplasia after balloon angioplasty in hypercholesterolemic rabbits
10. Proliferating cell nuclear antigen (PCNA) immunolocalization in paraffin sections: An index of cell proliferation with evidence of deregulated expression in some neoplasms
11. Low-dose radioactive endovascular stents prevent smooth muscle cell proliferation and neointimal hyperplasia in rabbits
12. 1 binding protein in human gastrointestinal carcinomas: Quantitative difference between cancer cells and stromal cells
13. Characterization of novel monoclonal antibodies raised against formalin-fixed, paraffin-embedded human ameloblastoma
14. A heritable hyperlipidemic rabbit
15. WHHL rabbit: A low density lipoprotein receptor-deficient animal model for familial hypercholesterolemia
16. Deficiency of LDL receptor in liver and adrenal gland of the WHHL rabbit
17. Receptor-mediated endocytosis: Insight from the lipoprotein receptor system
18. The role of antiplatelet agents in modifying the extent of restenosis following percutaneous transluminal coronary angioplasty
19. Effect of 18- to 24-hour heparin administration for prevention of restenosis after uncomplicated coronary angioplasty
20. Low molecular weight heparin in prevention of restenosis after angioplasty. Results of enoxaparin restenosis (ERA) trial
21. Effect of glycoprotein IIb/IIIa receptor blockade with abciximab on clinical and angiographic restenosis rate after the placement of coronary stents following acute myocardial infarction
22. The role of plasminogen activation in smooth muscle cell migration after arterial injury
23. Potentiation by hypercholesterolemia of the induction of aortic intramural synthesis of plasminogen activator inhibitor type 1 by endothelial injury
24. Regulation of arterial thrombolysis by plasminogen activator inhibitor-1 in mice
25. The endothelial cell tissue plasminogen activator receptor
26. Inhibition of endothelial cell movement by pericytes and smooth muscle cells: Activation of a latent transforming growth factor-β1-1ike molecule by plasmin during co-culture
27. Cellular mechanisms for human procollagenase-3 (MMP- 13) activation
28. Induction of plasminogen activator inhibitor by product released from platelets
29. 1 and heparin
30. Lipoprotein(a) inhibits the generation of transforming growth factor β: An endogenous inhibitor of smooth muscle cell migration
31. Growth factor expression in aorta of normotensive and hypertensive rots
32. Biological and biochemical properties of fibroblast growth factors
33. Endothelial cell-derived heparan sulfate binds basic fibroblast growth factor and protects it from proteolytic degradation