Human cervical tissue metabolizes the tobacco-specific nitrosamine, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, via α-hydroxylation and carbonyl reduction pathways

Carcinogenesis

Volumn 22, Issue 1, 2001, Pages 107-114

  Prokopczyk, Bogdan ^a   Trushin, Neil ^a   Leszczynska, Joanna ^a   Waggoner, Steven E ^b   El Bayoumy, Karam ^a  

^a AMERICAN HEALTH FOUNDATION   (United States)

^b UNIVERSITY OF CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

11BETA HYDROXYSTEROID DEHYDROGENASE; 4 (METHYLNITROSAMINO) 1 (3 PYRIDYL) 1 BUTANONE; BUTYRIC ACID DERIVATIVE; CARBONYL DERIVATIVE; CORTISONE; GLYCYRRHIZIC ACID; ISOCYANIC ACID DERIVATIVE; METYRAPONE; NITROSAMINE; OXOACID;

ARTICLE; CELL CULTURE; CELL METABOLISM; CHEMICAL REACTION KINETICS; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CYTOSOL; DERIVATIZATION; ENANTIOMER; EPITHELIUM CELL; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; HYDROXYLATION; METABOLIC REGULATION; MICROSOME; OXIDATION; PRIORITY JOURNAL; REDUCTION; STEREOCHEMISTRY; TISSUE METABOLISM; TOBACCO; TOXICITY TESTING; UTERINE CERVIX EPITHELIUM;

11-BETA-HYDROXYSTEROID DEHYDROGENASES; CARCINOGENS; CELL LINE; CERVIX UTERI; CORTISONE; CYTOSOL; FEMALE; GLYCYRRHIZIC ACID; HUMANS; HYDROCORTISONE; HYDROXYLATION; HYDROXYSTEROID DEHYDROGENASES; KETO ACIDS; KINETICS; METYRAPONE; MICROSOMES; NITROSAMINES; OXIDATION-REDUCTION; STEREOISOMERISM; TRITIUM;

EID: 0035136850     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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