Analysis of the promoter region of human cartilage oligomeric matrix protein (COMP)

Matrix Biology

Volumn 19, Issue 8, 2001, Pages 783-792

  Deere, Michelle ^a   Rhoades Hall, Catherine ^a   Gunning, Kerry B ^a   Lefebvre, Veronique ^b   Ridall, Amy L ^c   Hecht, Jacqueline T ^a,d  

^a UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^c UNIVERSITY OF TEXAS   (United States)

^d Shriners Hospital for Children   (United States)

Author keywords

Chondrocytes; EDM1; Gel shift; Ligament; Luciferase; Multiple epiphyseal dysplasia; Promoter; PSACH; Pseudoachondroplasia; Tendon; Thrombospondin

Indexed keywords

CALCIUM BINDING PROTEIN; CARTILAGE OLIGOMERIC MATRIX PROTEIN; DNA BINDING PROTEIN; MATRIX PROTEIN; PREGNANCY SPECIFIC BETA1 GLYCOPROTEIN; THROMBOSPONDIN; UNCLASSIFIED DRUG;

ARTICLE; CARTILAGE; CARTILAGE CELL; CELL CULTURE; CONTROLLED STUDY; DNA TRANSCRIPTION; GENE EXPRESSION; GENETIC ANALYSIS; HUMAN; HUMAN CELL; IN VITRO STUDY; LIGAMENT; MOLECULAR CLONING; NORMAL HUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; SEQUENCE ANALYSIS; TENDON;

BASE SEQUENCE; DNA PRIMERS; EXTRACELLULAR MATRIX PROTEINS; GENES, REPORTER; GLYCOPROTEINS; HUMANS; LUCIFERASES; MOLECULAR SEQUENCE DATA; PROMOTER REGIONS (GENETICS); SEQUENCE ANALYSIS, DNA;

EID: 0035135367     PISSN: 0945053X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0945-053X(00)00127-X     Document Type: Article

References (28)

1. Analysis of the promoter and transcription start sites of the human thrombospondin 2 gene
2. Structure and organization of the human thrombospondin 3 gene
3. Pseudoachondroplasia and multiple epiphyseal dysplasia due to mutations in the cartilage oligomeric matrix protein gene
4. SP1- binding elements, within the common metaxin-thrombospondin 3 intergenic region, participate in the regulation of the metaxin gene
5. Detection and characterization of SP1 binding activity in human chondrocytes and its alterations during chondrocyte differentiation
6. Cartilage oligomeric matrix protein (COMP) is an abundant component of tendon
7. The structure of the rat aggrecan gene and preliminary characterization of its promoter
8. Identification of a high-molecular-weight (>400,00) protein in hyaline cartilage
9. A serum response element and a binding site for NF-Y mediate the serum response of the human thrombospondin
10. Characterization of cartilage oligomeric matrix protein (COMP) in human normal and pseudoachondroplasia musculoskeletal tissues
11. Retention of cartilage oligomeric matrix protein and cell death in redifferentiated pseudoachondroplasia chondrocytes
12. Mutations in exon 17B of cartilage oligomeric matrix protein (COMP) cause pseudoachondroplasia
13. Chondrocyte-specific enhancer regions in the COMP gene
14. Characterization of mouse thrombospondin 2 sequence and expression during cell growth and development
15. Sox9 is a potent activator of the chondrocyte-specific enhancer of proa1(II) collagen gene
16. Natural history study of pseudaochondroplasia
17. Use of a new rat chondrosarcoma cell line to delineate a 119-base pair chondrocyte-specific enhancer element and to define active promoter segments in the mouse pro-alpha 1(II) collagen gene
18. Tissue-specific forms of type IX collagen-proteoglycan arise from the use of two widely separated promoters
19. Transcriptionall activation of the α1(VI) collagen gene during myoblast differentiation is mediated by multiple GA boxes
20. Characterization of a glucocorticoid responsive element and identification of an AT-rich element that regulate the link protein gene
21. Collagen II promoter and enhancer interact synergistically through Sp1 and distinct nuclear factors
22. The distribution of cartilage oligomeric matrix protein (COMP) in tendon and its variation with tendon site, age, and load
23. Sequence comparison of three mammalian type-X collagen promoters and preliminary functional analysis of the human promoter
24. Aggrecan in bovine tendon