Heterologous expression of lacticin 3147 in Enterococcus faecalis: Comparison of biological activity with cytolysin

Letters in Applied Microbiology

Volumn 32, Issue 2, 2001, Pages 71-77

  Ryan, M P ^a,b   McAuliffe, O ^a,b   Ross, R P ^a,b   Hill, C ^a,b  

^a ANIMAL AND GRASSLAND RESEARCH AND INNOVATION CENTRE   (Ireland)

^b UNIVERSITY COLLEGE CORK   (Ireland)

Author keywords

[No Author keywords available]

Indexed keywords

BACILLI; MEDICAL APPLICATIONS;

BACTERIOCINS; BROAD SPECTRUM; ENTEROCOCCUS FAECALIS; FOOD APPLICATIONS; HEMOLYTIC ACTIVITY; HETEROLOGOUS EXPRESSION; LACTICIN; LACTOCOCCUS LACTIS; LANTHIONINES; TWO-COMPONENT;

BIOACTIVITY;

BACTERIOCIN; CYTOLYSIN; LACTICIN 3147; LANTHIONINE; LANTIBIOTIC; STAPHYLOCOCCIN C55; UNCLASSIFIED DRUG;

ANTIMICROBIAL ACTIVITY; ARTICLE; ELECTROPORATION; ENTEROCOCCUS FAECALIS; FOOD SAFETY; HEMOLYSIS; LACTOCOCCUS LACTIS; NONHUMAN; PLASMID; STAPHYLOCOCCUS AUREUS;

BACTERIA (MICROORGANISMS); ENTEROCOCCUS FAECALIS; EQUIDAE; LACTOCOCCUS LACTIS; POSIBACTERIA; STAPHYLOCOCCUS AUREUS; STREPTOCOCCUS;

EID: 0035135297     PISSN: 02668254     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1472-765X.2001.00864.x     Document Type: Article

References (12)

1. Simple and rapid method for isolating large plasmid DNA from lactic streptococci
2. Structural analysis and proteolytic activation of Enterococcus faecalis cytolysin, a novel lantibiotic
3. Probable identity of a group D haemolysin with a bacteriocine
4. Sequence and analysis of the 60 kb conjugative, bacteriocin-producing plasmid pMRC01 from Lactococcus lactis DPC3147
5. Improved electroporation and cloning vector system for Gram-positive bacteria
6. Inhibition of Listeria monocytogenes in cottage cheese manufactured with a lacticin 3147 producing starter culture
7. Identification and overexpression of ltnI, a novel gene which confers immunity to the two component lantibiotic, lacticin 3147
8. Each peptide of the two component lantibiotic lacticin 3147 requires a separate modification enzyme for activity
9. Identification of genes encoding two-component lantibiotic production in Staphylococcus aureus C55 and other phage group II S. aureus strains and demonstration of an association with the exfoliative toxin B gene
10. Developing applications for lactococcal bacteriocins, examples using the broad spectrum lacticin 3147 and the narrow spectrum lactococcins A, B and M
11. Extensive post-translational modification including serine to D-alanine conversion in the two-component lantibiotic, lacticin 3147
12. An application in Cheddar cheese manufacture for a strain of Lactococcus lactis producing a novel broad spectrum bacteriocin, lacticin 3147