Formation of non-resorbing osteoclasts from peripheral blood mononuclear cells of patients with malignant juvenile osteopetrosis

British Journal of Haematology

Volumn 112, Issue 1, 2001, Pages 64-68

  Gerritsen, E J A ^a   Helfrich, Miep ^a,b  

^a UNIVERSITY OF ABERDEEN   (United Kingdom)

^b Medisch Centrum Rijnmond Zuid   (Netherlands)

Author keywords

Bone resorption; Osteoclast; Osteopetrosis; Peripheral blood precursor; Ultrastructure

Indexed keywords

ALBERS SCHOENBERG DISEASE; ARTICLE; BONE BIOPSY; CASE REPORT; FEMALE; HUMAN; HUMAN CELL; INFANT; MONONUCLEAR CELL; OSTEOCLAST; OSTEOLYSIS; PRIORITY JOURNAL;

ANIMALS; BONE AND BONES; BONE RESORPTION; CELL DIFFERENTIATION; CELLS, CULTURED; COCULTURE TECHNIQUES; FEMALE; HUMANS; INFANT; LEUKOCYTES, MONONUCLEAR; MICE; MODELS, BIOLOGICAL; OSTEOCLASTS; OSTEOPETROSIS;

EID: 0035134408     PISSN: 00071048     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2141.2001.02538.x     Document Type: Article

References (12)

1. Study of the nonresorptive phenotype of osteoclast-like cells from patients with malignant osteopetrosis: A new approach to investigating pathogenesis
2. Defects in TCIRG1 subunit of the vacuolar proton pump are responsible for a subset of human autosomal recessive osteopetrosis
3. Bone marrow transplantation for autosomal recessive osteopetrosis. A report from the Working Party on Inborn Errors of the European Bone Marrow Transplantation Group
4. Autosomal recessive osteopetrosis: Variability of findings at diagnosis and during the natural course
5. Osteoclast generation from human fetal bone marrow in co-cultures with murine fetal long bones. A model for in vitro study of human osteoclast formation and function
6. Morphologic features of bone in human osteopetrosis
7. Localization of RANKL (receptor activator of NFkappaB ligand) mRNA and protein in skeletal and extraskeletal tissues
8. The heterogeneity of the osteopetroses reflects the diversity of cellular influences during skeletal development
9. A combination of osteoclast differentiation factor and macrophage-colony stimulating factor is sufficient for both human and mouse osteoclast formation in vitro
10. In vitro osteoclast generation from different bone marrow fractions, including a highly enriched haematopoietic stem cell population
11. Mechanisms of osteoclast dysfunction in human osteopetrosis: Abnormal osteoclastogenesis and lack of osteoclast-specific adhesion structures
12. Sclerosing bone disorders