GTP-binding protein Gq mediates muscarinic-receptor-induced inhibition of the inwardly rectifying potassium channel IRK1 (Kir 2.1)

Neuropharmacology

Volumn 40, Issue 3, 2001, Pages 358-365

  Firth, Tracy A ^a   Jones, S V Penelope ^a,b  

^a UNIVERSITY OF VERMONT   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

G proteins; Kir 2.1; Muscarinic receptor; Potassium channel; Signal transduction

Indexed keywords

CARBACHOL; COMPLEMENTARY DNA; GENE PRODUCT; GQ PROTEIN; GUANINE NUCLEOTIDE BINDING PROTEIN; MUSCARINIC M1 RECEPTOR; POTASSIUM CHANNEL; PROTEIN IRK1; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; POTASSIUM CURRENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FAMILY; SIGNAL TRANSDUCTION;

BLOTTING, WESTERN; CARBACHOL; CELL LINE; DNA-BINDING PROTEINS; DOSE-RESPONSE RELATIONSHIP, DRUG; GTP-BINDING PROTEIN ALPHA SUBUNITS, G12-G13; GTP-BINDING PROTEIN ALPHA SUBUNITS, GQ-G11; HETEROTRIMERIC GTP-BINDING PROTEINS; HUMANS; MEMBRANE POTENTIALS; POTASSIUM CHANNEL BLOCKERS; POTASSIUM CHANNELS; POTASSIUM CHANNELS, INWARDLY RECTIFYING; PROTEIN SUBUNITS; RECEPTOR, MUSCARINIC M1; RECEPTORS, MUSCARINIC; TRANSFECTION;

EID: 0035133678     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0028-3908(00)00161-1     Document Type: Article

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