Bax-induced apoptosis not demonstrated in the congenital toxoplasmosis in mice

Brain and Development

Volumn 23, Issue 1, 2001, Pages 50-53

  Takahashi, Junko ^a,b   Fukuda, Takahiro ^a   Tanaka, Junichi ^a   Minamitani, Motoyuki ^a   Onouchi, Kenji ^a   Makioka, Asao ^a  

^a JIKEI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

Author keywords

Apoptosis; Bax; Bcl 2; Cerebral cortical hypoplasia; Toxoplasmosis

Indexed keywords

PARAFFIN; PROTEIN BAX; PROTEIN BCL 2;

AGE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONGENITAL TOXOPLASMOSIS; CONTROLLED STUDY; CORTICAL DYSPLASIA; DEPLETION; EMBRYO; FEMALE; FETUS; HYPOPLASIA; IMMUNOHISTOCHEMISTRY; MOUSE; NEUROPATHOLOGY; NICK END LABELING; NONHUMAN; TOXOPLASMA GONDII;

ANIMALS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BODY PATTERNING; CEREBRAL CORTEX; FEMALE; FETUS; MICE; MICE, INBRED C57BL; NERVOUS SYSTEM MALFORMATIONS; NEURONS; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; TOXOPLASMA; TOXOPLASMOSIS, ANIMAL; TOXOPLASMOSIS, CEREBRAL; TOXOPLASMOSIS, CONGENITAL;

EID: 0035132477     PISSN: 03877604     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0387-7604(01)00179-6     Document Type: Article

References (23)

1. Toxoplasmosis
2. Cataract in mice congenitally infected with Toxoplasma gondii
3. A study of cataract in murine congenital toxoplasmosis
4. Pathomechanism of cerebral hypoplasia in experimental toxoplasmosis in murine fetuses
5. Regressive events in neurogenesis
6. Cell death during development of the nervous system
7. The proto-oncogene Bcl-2 and its role in regulating apoptosis
8. Immunohistochemical determination of in vivo distribution of Bax, a dominant inhibitor of Bcl-2
9. Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation
10. Perspective: virus infections and the death of neurons
11. Radiation-induced apoptosis and limb teratogenesis in embryonic mice
12. Toxoplasma gondii: blood and tissue kinetics during acute and chronic infections in mice
13. Congenital toxoplasmosis. A prospective study of 378 pregnancies
14. Cerebral anomalies in congenital murine toxoplasmosis: a preliminary report
15. The effect of cytokines on the replication of T. gondii within rat retinal vascular endothelial cells
16. Interferon-gamma receptor-mediated but not tumor necrosis factor receptor type 1- or type 2-mediated signaling is crucial for the activation of cerebral blood vessel endothelial cells and microglia in murine Toxoplasma encephalitis
17. Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death
18. Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells
19. bcl-2 messenger RNA is localized in neurons of the developing and adult rat brain
20. Increased expression of bcl-2 immunoreactivity in the developing cerebral cortex of the rat
21. Up-regulation of bax and down-regulation of bcl-2 is associated with kainate-induced apoptosis in mouse brain
22. Immunohistochemical detection of Bax and Bcl-2 proteins in gerbil hippocampus following transient forebrain ischemia
23. Bcl-2 protein expression during murine development